{"id":"W2903962322","doi":"10.1182/blood-2018-99-112988","title":"A Global, Randomized, Placebo-Controlled, Phase 3 Study of Ibrutinib Plus Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone (RCHOP) in Patients with Previously Untreated Non-Germinal Center B-Cell-like (GCB) Diffuse Large B-Cell Lymphoma (DLBCL)","year":2018,"lang":"en","type":"article","venue":"Blood","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Spinal Cord Injury BC; University of British Columbia","funders":"","keywords":"Ibrutinib; Vincristine; Rituximab; Medicine; Prednisone; Cyclophosphamide; Internal medicine; Phases of clinical research; Nuclear medicine; Oncology; Surgery; Chemotherapy; Lymphoma; Leukemia; Chronic lymphocytic leukemia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001977289,0.001657184,0.003080886,0.0005125813,0.0004163107,0.001132059,0.001041171,0.001439607,0.005027481],"category_scores_gemma":[0.0009660301,0.0007875774,0.001752187,0.0005429356,0.001452155,0.0008936415,0.0004459964,0.002756269,0.0009868771],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000731533,"about_ca_system_score_gemma":0.001397448,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007312657,"about_ca_topic_score_gemma":0.002514736,"domain_scores_codex":[0.999275,0.000383067,0.00003409225,0.0001526749,0.00004153954,0.0001135986],"domain_scores_gemma":[0.9993469,0.0001353388,0.0001524714,0.00006069402,0.00004941278,0.0002550965],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9652905,0.01168776,0.0008978017,0.0005342252,0.001044569,0.00004042017,0.00004831133,0.0002925209,0.005696131,0.00005684323,0.0005629755,0.01384794],"study_design_scores_gemma":[0.9188998,0.07798228,0.001803944,0.00001494605,0.0004236204,0.00002208893,0.00001133502,0.000132804,0.0002826262,0.00005179687,0.0003663368,0.000008424239],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9850215,0.005361527,0.0007214998,0.0005162517,0.0004010284,0.0048084,0.001058859,0.0001620659,0.001948855],"genre_scores_gemma":[0.9863968,0.002638072,0.001466136,0.001190907,0.0003966422,0.004610079,0.001137969,0.00003231093,0.002130996],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005027481,"threshold_uncertainty_score":0.01681858,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004923132404732803,"score_gpt":0.2569880009048837,"score_spread":0.2520648685001509,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}