{"id":"W2904001710","doi":"10.1016/j.yhbeh.2018.12.007","title":"Pubertal development of estradiol-induced hypothalamic progesterone synthesis","year":2018,"lang":"en","type":"article","venue":"Hormones and Behavior","topic":"Hypothalamic control of reproductive hormones","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia Hospital","funders":"Clinical and Translational Science Institute, University of California, Los Angeles; Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Center for Advancing Translational Sciences; Canadian Institutes of Health Research","keywords":"Internal medicine; Endocrinology; Kisspeptin; Estrogen; Luteinizing hormone; Hypothalamus; Ovulation; Precocious puberty; Hypothalamic–pituitary–gonadal axis; Ovariectomized rat; Gonadotropin-releasing hormone; Biology; Hormone; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002069727,0.0002509507,0.0002236789,0.000609713,0.0003942292,0.0007756833,0.0002786783,0.000246331,0.004902441],"category_scores_gemma":[0.0006076864,0.0003219346,0.0001882596,0.0002460202,0.0003938283,0.0003695618,0.0004884637,0.0005606028,0.0005872239],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004788346,"about_ca_system_score_gemma":0.0008753192,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002782221,"about_ca_topic_score_gemma":0.005266872,"domain_scores_codex":[0.9998693,0.00001977779,0.000006141136,0.00003017669,0.00003714928,0.00003731271],"domain_scores_gemma":[0.9995995,0.00007701208,0.00008660816,0.00003415826,0.00006004586,0.0001426472],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.004260334,0.0003130675,0.03095505,0.0001802626,0.00006148821,0.001361697,0.0007828379,0.0001879565,0.9187547,0.003861853,0.0009490025,0.03833173],"study_design_scores_gemma":[0.0001044968,0.0005773979,0.5402884,0.0001118526,0.00008078899,0.0009236208,0.0006179963,0.0003672111,0.4395107,0.0007038404,0.01669098,0.00002276086],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9857299,0.004023711,0.001350485,0.0002615674,0.00009429556,0.00003300333,0.0009860697,0.000102245,0.007418816],"genre_scores_gemma":[0.9917232,0.001561151,0.0005929599,0.00007276105,0.00002618279,0.00003208587,0.000558024,0.00004338107,0.005390267],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004902441,"threshold_uncertainty_score":0.01640034,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03288484967833318,"score_gpt":0.2790521225898988,"score_spread":0.2461672729115656,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}