{"id":"W2904097792","doi":"10.1152/physrev.00065.2017","title":"Innate Immune Signaling and Its Role in Metabolic and Cardiovascular Diseases","year":2018,"lang":"en","type":"review","venue":"Physiological Reviews","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":97,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Innate immune system; Biology; Immune system; Innate lymphoid cell; Inflammation; Pattern recognition receptor; Immunology; CCL18; Toll-like receptor; Acquired immune system; Transcription factor; Cell biology; Signal transduction; Receptor; Classical complement pathway; Genetics; Gene; Complement system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001011405,0.0005033484,0.003912359,0.0001563661,0.0001257569,0.00002352902,0.0002492023,0.0004855348,0.0001425591],"category_scores_gemma":[0.0007177221,0.0003070152,0.0008231942,0.0002533036,0.0001814615,0.0001130911,0.0002979811,0.0004784268,0.0006012753],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001706953,"about_ca_system_score_gemma":0.00004353984,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00000939945,"about_ca_topic_score_gemma":2.905167e-7,"domain_scores_codex":[0.9955696,0.002361216,0.001018481,0.0006248764,0.00003817892,0.000387624],"domain_scores_gemma":[0.9989327,0.0002317282,0.0003424684,0.0004216677,0.0000372773,0.00003414858],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00003086034,0.00005423207,0.000001552121,0.004968815,0.000565564,0.000005237492,0.00005090009,1.968243e-7,0.004531915,0.0003041677,0.0003072148,0.9891794],"study_design_scores_gemma":[0.000236736,0.00007957352,0.0001627702,0.004737888,0.0009068739,0.00003039246,0.000006930109,8.869011e-7,0.0001781939,0.0001068656,0.9932067,0.0003462358],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.002328087,0.9962496,0.000001751984,0.000004934912,0.0001331868,0.001205628,0.00001614916,0.00003097216,0.00002972146],"genre_scores_gemma":[0.001018677,0.9981818,0.00001099636,0.00002895174,0.00008393821,0.0003376183,0.0002142929,0.00002271762,0.0001010169],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9928994,"threshold_uncertainty_score":0.9999382,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04988921042411643,"score_gpt":0.3035108481675978,"score_spread":0.2536216377434813,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}