{"id":"W2904097792","doi":"10.1152/physrev.00065.2017","title":"Innate Immune Signaling and Its Role in Metabolic and Cardiovascular Diseases","year":2018,"lang":"en","type":"review","venue":"Physiological Reviews","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":97,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Innate immune system; Biology; Immune system; Innate lymphoid cell; Inflammation; Pattern recognition receptor; Immunology; CCL18; Toll-like receptor; Acquired immune system; Transcription factor; Cell biology; Signal transduction; Receptor; Classical complement pathway; Genetics; Gene; Complement system","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004934554,0.0004713067,0.0005718441,0.0006559669,0.0004101694,0.0009436323,0.0003784342,0.0009571754,0.002666909],"category_scores_gemma":[0.0004089058,0.0001154219,0.0004330406,0.0006961839,0.0006714909,0.0006200608,0.0007933336,0.001652751,0.0006729329],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004946143,"about_ca_system_score_gemma":0.000805497,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008639403,"about_ca_topic_score_gemma":0.0005882106,"domain_scores_codex":[0.9996974,0.00007661729,0.00002967905,0.00006836042,0.0000706051,0.0000573958],"domain_scores_gemma":[0.9998313,0.00003028146,0.00004283716,0.000008611134,0.00004887643,0.00003815453],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.001314571,0.0003885381,0.008341121,0.009385503,0.0004376752,0.002932262,0.0009296993,0.001338249,0.1014445,0.09518332,0.05457121,0.7237334],"study_design_scores_gemma":[0.0001098522,0.0007148637,0.03759239,0.003155747,0.0004591602,0.007483942,0.0007930206,0.001711249,0.01540398,0.06177176,0.8706465,0.0001575034],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.007847009,0.9797689,0.001997642,0.003652262,0.001050375,0.00001634624,0.0001563233,0.00004038363,0.005470666],"genre_scores_gemma":[0.156887,0.825217,0.002750757,0.00323984,0.003284108,0.00008995259,0.0003661611,0.00001734483,0.008147904],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002666909,"threshold_uncertainty_score":0.008921742,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04988921042411643,"score_gpt":0.3035108481675978,"score_spread":0.2536216377434813,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}