{"id":"W2904219708","doi":"10.1016/j.msard.2018.10.087","title":"Alemtuzumab Improves Clinical and Radiological Outcomes in Patients with Relapsing-remitting Multiple Sclerosis Over 8 Years: Care-MS I Follow-up (topaz Study)","year":2018,"lang":"en","type":"article","venue":"Multiple Sclerosis and Related Disorders","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"NeuroRx Research (Canada)","funders":"","keywords":"Alemtuzumab; Medicine; Multiple sclerosis; Radiological weapon; Clinical trial; Internal medicine; Physical therapy; Surgery; Psychiatry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004655059,0.0003741874,0.0008054219,0.0001998408,0.0003168773,0.00006701685,0.0001423463,0.0003405683,0.00005537827],"category_scores_gemma":[0.000604965,0.00024961,0.0001737079,0.0003286167,0.0009399657,0.0001526764,0.0002439652,0.000700127,0.00001445024],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005068157,"about_ca_system_score_gemma":0.00004921688,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001251721,"about_ca_topic_score_gemma":0.0008904207,"domain_scores_codex":[0.9970512,0.0002261547,0.0007637809,0.0008457617,0.0004982178,0.0006148961],"domain_scores_gemma":[0.9985422,0.0005145232,0.0001574544,0.0003245885,0.0001374798,0.0003237596],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002279992,0.0008981067,0.9494949,0.00003707584,0.0002774474,0.00000563455,0.002283544,0.000002165451,0.0002454756,0.000004534038,0.00009472063,0.0443764],"study_design_scores_gemma":[0.02676925,0.003406459,0.9665725,0.0003238874,0.0001108579,0.000001864818,0.001511913,0.0006204931,0.00001600407,0.00001477665,0.0003148629,0.0003371677],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968396,0.0009619425,0.00000341792,0.0002381941,0.000347846,0.001266748,0.0000283914,0.00006725352,0.0002465749],"genre_scores_gemma":[0.9979879,0.00102086,0.0003474794,0.0001579225,0.00007201726,0.00003736293,0.00004908339,0.00004887781,0.0002785229],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04403923,"threshold_uncertainty_score":0.9999956,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03784702482552056,"score_gpt":0.2893418422662811,"score_spread":0.2514948174407605,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}