{"id":"W2904270864","doi":"10.1016/j.cllc.2018.12.009","title":"Effect of Coexisting KRAS and TP53 Mutations in Patients Treated With Chemotherapy for Non–small-cell Lung Cancer","year":2018,"lang":"en","type":"article","venue":"Clinical Lung Cancer","topic":"Lung Cancer Treatments and Mutations","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":false,"ca_institutions":"University Health Network; University of Toronto; Princess Margaret Cancer Centre","funders":"","keywords":"KRAS; Medicine; Internal medicine; Hazard ratio; Oncology; Lung cancer; Chemotherapy; Clinical endpoint; Confidence interval; Cancer; Gastroenterology; Clinical trial; Colorectal cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004333538,0.0002483312,0.0006082663,0.000245667,0.0003614114,0.0006279605,0.0002297828,0.0005535935,0.002212023],"category_scores_gemma":[0.002924829,0.0001649006,0.001102003,0.0003599179,0.0003820085,0.0005529525,0.0003472528,0.0007750918,0.000125021],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00048818,"about_ca_system_score_gemma":0.0005296925,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002047818,"about_ca_topic_score_gemma":0.004817177,"domain_scores_codex":[0.9995614,0.0001777916,0.00003564382,0.00008124871,0.00004244372,0.0001014938],"domain_scores_gemma":[0.9986507,0.000571572,0.0003035559,0.00005087549,0.0000614117,0.0003618903],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.04579142,0.0006598999,0.9277942,0.00008065251,0.00102207,0.0006969829,0.00009981525,0.0003947344,0.004113115,0.0001461804,0.0003679733,0.0188329],"study_design_scores_gemma":[0.0003970549,0.005479656,0.9908598,0.00002059672,0.0008981999,0.0004843438,0.0002030279,0.0004455279,0.0003587571,0.0001321007,0.0007068471,0.00001404282],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979635,0.0009721444,0.00002320993,0.0001273301,0.00002738347,0.000005893301,0.00006981605,0.000002524282,0.0008080802],"genre_scores_gemma":[0.999479,0.0001508476,0.00002300944,0.0000485802,0.0000272518,0.000002909402,0.00007821176,0.000001237604,0.0001887979],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002212023,"threshold_uncertainty_score":0.007399917,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01921747637091618,"score_gpt":0.4167759382705536,"score_spread":0.3975584618996374,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}