{"id":"W2904696250","doi":"10.1007/s00204-018-2370-1","title":"Re: Gi et al. 2018, In vivo positive mutagenicity of 1,4-dioxane and quantitative analysis of its mutagenicity and carcinogenicity in rats, Archives of Toxicology 92:3207–3221","year":2018,"lang":"en","type":"letter","venue":"Archives of Toxicology","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"Health Canada","funders":"","keywords":"In vivo; Carcinogen; Toxicology; Chemistry; Pharmacology; Biology; Genetics; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001173272,0.0006362491,0.0008504656,0.0005775259,0.001448113,0.001824078,0.001024395,0.02253682,0.01150602],"category_scores_gemma":[0.01013738,0.000356579,0.0006109858,0.0003345257,0.00103356,0.001560087,0.0007904379,0.01883427,0.01793564],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002132692,"about_ca_system_score_gemma":0.001169389,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002130602,"about_ca_topic_score_gemma":0.004435075,"domain_scores_codex":[0.9993349,0.0001166564,0.0000850697,0.00009561871,0.0002572472,0.000110616],"domain_scores_gemma":[0.9978907,0.0007167408,0.0001718294,0.00009856459,0.0008591183,0.0002632232],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005827886,0.00003823662,0.0003730824,0.00004098991,0.000007217534,0.001573775,0.00002921056,0.00002188632,0.0001799311,0.0005195072,0.9875863,0.009571616],"study_design_scores_gemma":[0.00008385981,0.00006557596,0.001216136,0.0001754086,0.00002152226,0.003159265,0.0001591682,0.0001988079,0.000455494,0.003194671,0.9912391,0.00003089196],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.001006578,0.00317494,0.0002451482,0.9103356,0.07578806,0.00002322069,0.0002525675,0.0001638737,0.009009993],"genre_scores_gemma":[0.007907008,0.00340518,0.0004626283,0.826654,0.1115959,0.00006898498,0.0002357362,0.00006200627,0.04960864],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.02253682,"threshold_uncertainty_score":0.03849149,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01702880681404574,"score_gpt":0.2934815209418999,"score_spread":0.2764527141278542,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}