{"id":"W2904759668","doi":"10.1212/wnl.88.16_supplement.s12.006","title":"Alemtuzumab Decreased MRI Disease Activity Through 6 Years in Patients With Highly Active RRMS and an Inadequate Response to Prior Therapy: CARE-MS II Extension Study (S12.006)","year":2017,"lang":"en","type":"article","venue":"Neurology","topic":"Polyomavirus and related diseases","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"NeuroRx Research (Canada); Montreal Neurological Institute and Hospital; McGill University; University of British Columbia","funders":"","keywords":"Medicine; Alemtuzumab; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001152276,0.0005430099,0.0008460484,0.0002747717,0.0003015409,0.0005104321,0.0004125727,0.0005253917,0.001029102],"category_scores_gemma":[0.00145501,0.0002047912,0.0006757595,0.0003566096,0.0002186518,0.0004941247,0.000327898,0.0007632112,0.0002283512],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004011461,"about_ca_system_score_gemma":0.0005283094,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002183969,"about_ca_topic_score_gemma":0.003282401,"domain_scores_codex":[0.9996849,0.000121175,0.00002680639,0.00006896367,0.00003366667,0.00006436642],"domain_scores_gemma":[0.9991048,0.0001066981,0.0003482518,0.00005814369,0.0001025536,0.0002795545],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.3124363,0.01041327,0.5784291,0.0005018354,0.00362713,0.0003255004,0.0004575015,0.001038357,0.01191978,0.00009775918,0.002311442,0.07844203],"study_design_scores_gemma":[0.0224788,0.09565647,0.8750098,0.00007019082,0.001929946,0.0004674444,0.0001373713,0.0008208881,0.001772285,0.0001024609,0.001518691,0.00003567037],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9988906,0.0005037811,0.00002997583,0.00003200022,0.000008233964,0.00004282797,0.0002299985,0.000005696319,0.0002569389],"genre_scores_gemma":[0.9983016,0.0002389932,0.0001561979,0.00008515544,0.00004108818,0.00004701775,0.0007885132,0.000002943484,0.000338482],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002183969,"threshold_uncertainty_score":0.006093919,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01507045994091256,"score_gpt":0.2988587173356254,"score_spread":0.2837882573947129,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}