{"id":"W2904760236","doi":"10.3389/fnmol.2018.00463","title":"Transcriptomic Analysis of Zebrafish TDP-43 Transgenic Lines","year":2018,"lang":"en","type":"article","venue":"Frontiers in Molecular Neuroscience","topic":"Amyotrophic Lateral Sclerosis Research","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Canadian Institutes of Health Research; ALS Society of Canada","keywords":"Zebrafish; TARDBP; Biology; Amyotrophic lateral sclerosis; Transgene; Gene; Mutant; Spinal muscular atrophy; Mutation; Cell biology; Genetics; Molecular biology; SOD1; Pathology; Disease; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0000866461,0.0003728845,0.000266424,0.0006241728,0.000231635,0.00020538,0.0001598554,0.0002407526,0.001411982],"category_scores_gemma":[0.0001243383,0.0001715298,0.0003469152,0.0003257304,0.0002195783,0.0001141324,0.0001838264,0.0004251498,0.0005705038],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000375088,"about_ca_system_score_gemma":0.0002732828,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001731162,"about_ca_topic_score_gemma":0.002499001,"domain_scores_codex":[0.9998403,0.000006367798,0.00001063273,0.00005648132,0.00005976436,0.00002650586],"domain_scores_gemma":[0.9998709,0.00002183026,0.00004625059,0.000007521965,0.00002958765,0.00002390982],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001971226,0.000003695213,0.0001329457,0.0000173795,0.000002600405,0.00004941792,0.00001326736,0.00002391804,0.999347,0.00002306972,0.00001589964,0.0003510192],"study_design_scores_gemma":[0.00002071661,0.0003049217,0.04074766,0.00002717222,0.00007260119,0.0005525138,0.000109413,0.001006658,0.9520014,0.0000960572,0.005037325,0.00002343909],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9567826,0.001375587,0.01909509,0.0001994749,0.00008932289,0.0001955646,0.01805749,0.0004137451,0.003791029],"genre_scores_gemma":[0.937117,0.002452087,0.02286561,0.0003504458,0.00003177112,0.000672808,0.02204174,0.0003816721,0.01408691],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001731162,"threshold_uncertainty_score":0.004723549,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02017113693823797,"score_gpt":0.2944148801170037,"score_spread":0.2742437431787657,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}