{"id":"W2904775252","doi":"10.1093/humrep/dey340","title":"JUNO, the receptor of sperm IZUMO1, is expressed by the human oocyte and is essential for human fertilisation","year":2018,"lang":"en","type":"article","venue":"Human Reproduction","topic":"Sperm and Testicular Function","field":"Medicine","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"Agence Nationale de la Recherche","keywords":"Gamete; Oocyte; Fertilisation; Monoclonal antibody; Biology; HEK 293 cells; Antibody; Molecular biology; Recombinant DNA; Sperm; Cell biology; Receptor; Reproductive technology; Genetics; Gene; Cryopreservation; Embryo","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005761071,0.0001901227,0.0003911766,0.0002021678,0.000271507,0.0003905774,0.0003363042,0.0004960055,0.005121326],"category_scores_gemma":[0.0005758807,0.0001474209,0.0002992726,0.0001645936,0.0003143705,0.0003161845,0.0002889624,0.0003542666,0.0008533896],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002325265,"about_ca_system_score_gemma":0.0004201925,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00023688,"about_ca_topic_score_gemma":0.0002453103,"domain_scores_codex":[0.9997469,0.00005531846,0.00002299915,0.00006977839,0.00005380899,0.00005131503],"domain_scores_gemma":[0.999688,0.00006503938,0.0001209042,0.00001608273,0.00004170452,0.00006818391],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003455507,0.0002063398,0.01762455,0.002170588,0.00006151466,0.0008777487,0.0001884339,0.0001107103,0.938759,0.001088923,0.001250032,0.03420661],"study_design_scores_gemma":[0.0007002243,0.006954371,0.2787643,0.0004805761,0.0005319875,0.01285242,0.001224233,0.001310353,0.6039004,0.00164672,0.09156603,0.00006826179],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9397202,0.04452448,0.00553262,0.001366774,0.0003250921,0.0004115321,0.0007835479,0.00005643945,0.00727932],"genre_scores_gemma":[0.972129,0.01632496,0.004678965,0.0006554874,0.0002907121,0.0003157523,0.0009307243,0.0000239908,0.004650358],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005121326,"threshold_uncertainty_score":0.01713252,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03320847960629834,"score_gpt":0.3028238291944088,"score_spread":0.2696153495881104,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}