{"id":"W2904775252","doi":"10.1093/humrep/dey340","title":"JUNO, the receptor of sperm IZUMO1, is expressed by the human oocyte and is essential for human fertilisation","year":2018,"lang":"en","type":"article","venue":"Human Reproduction","topic":"Sperm and Testicular Function","field":"Medicine","cited_by":53,"is_retracted":false,"has_abstract":true,"ca_institutions":"Canada Research Chairs; University of Toronto","funders":"Agence Nationale de la Recherche","keywords":"Gamete; Oocyte; Fertilisation; Monoclonal antibody; Biology; HEK 293 cells; Antibody; Molecular biology; Recombinant DNA; Sperm; Cell biology; Receptor; Reproductive technology; Genetics; Gene; Cryopreservation; Embryo","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005050993,0.0001488244,0.0001880227,0.00006085616,0.0007646782,0.00003884827,0.000085039,0.00008448026,0.0005464308],"category_scores_gemma":[0.0001326492,0.00009565346,0.00009128951,0.0001257434,0.0003815983,0.00009273104,0.00003160398,0.0001221455,0.0000128481],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003975057,"about_ca_system_score_gemma":0.00001567317,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001754371,"about_ca_topic_score_gemma":0.00003008978,"domain_scores_codex":[0.9986729,0.00005613007,0.0003194993,0.0005293974,0.0002587507,0.0001633251],"domain_scores_gemma":[0.9986333,0.00002643121,0.0002043673,0.0007920916,0.0003048771,0.00003889369],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000166033,0.0001049418,0.001222126,0.00006695186,0.00006092939,1.361703e-7,0.002224683,2.085404e-7,0.9391301,0.0005194481,0.05410627,0.002398166],"study_design_scores_gemma":[0.001265384,0.0006737885,0.04269401,0.00005731848,0.0002843981,0.00002275341,0.0004910446,0.00003490764,0.909866,0.001367902,0.04310779,0.0001347066],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9948014,0.0002509409,0.0002148566,0.002626639,0.0004742032,0.0008967036,0.00001106015,0.00006016765,0.00066402],"genre_scores_gemma":[0.9927657,0.00001539273,0.00006175919,0.0002222347,0.002495868,0.00006164183,0.0001203623,0.00002905361,0.004228004],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04147188,"threshold_uncertainty_score":0.5983034,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03320847960629834,"score_gpt":0.3028238291944088,"score_spread":0.2696153495881104,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}