{"id":"W2904820505","doi":"10.1039/c8tb02772b","title":"Zwitterionic shielded polymeric prodrug with folate-targeting and pH responsiveness for drug delivery","year":2018,"lang":"en","type":"article","venue":"Journal of Materials Chemistry B","topic":"Advanced Polymer Synthesis and Characterization","field":"Chemistry","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Soochow University; University of Waterloo; Government of Jiangsu Province; Natural Science Foundation of Jiangsu Province; National Natural Science Foundation of China","keywords":"Prodrug; Lewis acids and bases; Polymer; Drug delivery; Drug; Shielded cable; Combinatorial chemistry; Chemistry; Polymer chemistry; Materials science; Pharmacology; Organic chemistry; Biochemistry; Medicine; Catalysis; Computer science","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002692991,0.0002009817,0.0003658431,0.00002623925,0.0001420901,0.00009730844,0.0001725594,0.00009115858,0.000572663],"category_scores_gemma":[0.00009341152,0.0001591661,0.00005385735,0.00005302205,0.0001031491,0.000243234,0.00004316793,0.00008487249,0.000001346554],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003964429,"about_ca_system_score_gemma":0.0001047563,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003535364,"about_ca_topic_score_gemma":3.639892e-7,"domain_scores_codex":[0.9988229,0.00002264297,0.0005209903,0.0002032651,0.0001721402,0.0002581101],"domain_scores_gemma":[0.998598,0.0001004079,0.0007863832,0.0001634007,0.0002481223,0.0001036827],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001812494,0.00003483678,0.000148309,0.0003687194,0.00006081869,0.0000107332,0.0002784817,4.057255e-7,0.9959815,0.000002033791,0.00008241885,0.001219223],"study_design_scores_gemma":[0.0007849635,0.00006096793,0.00008976331,0.0003501066,0.00007116974,0.0001511905,0.0003362356,0.000005468901,0.9958531,0.00004888316,0.002045614,0.0002024943],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987749,0.0004224564,0.000230179,0.0001753033,0.0001523932,0.0000543307,0.00003768318,0.00001952615,0.0001331601],"genre_scores_gemma":[0.9970966,0.00009596568,0.0009759277,0.00005429349,0.001235679,0.00001173115,0.00001921638,0.00004090272,0.0004696577],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001963195,"threshold_uncertainty_score":0.6490607,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006636983948150415,"score_gpt":0.2202136421653619,"score_spread":0.2135766582172114,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}