{"id":"W2904974029","doi":"10.1021/acs.bioconjchem.8b00731","title":"Comparative Antigenicity of Thiourea and Adipic Amide Linked Neoglycoconjugates Containing Modified Oligomannose Epitopes for the Carbohydrate-Specific anti-HIV Antibody 2G12","year":2018,"lang":"en","type":"article","venue":"Bioconjugate Chemistry","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; Austrian Science Fund; Government of Canada; National Institutes of Health; Michael Smith Health Research BC","keywords":"Chemistry; Epitope; Glycan; Stereochemistry; Bovine serum albumin; Biochemistry; Antibody; Glycoprotein","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000157454,0.0003412978,0.0001016643,0.0002033191,0.00007919029,0.0001430128,0.0001270662,0.0001632132,0.001160415],"category_scores_gemma":[0.0002004268,0.000122006,0.0001036091,0.0001742588,0.0001179507,0.0001104493,0.0000948275,0.0001755098,0.0002154671],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002017944,"about_ca_system_score_gemma":0.00008445481,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004515013,"about_ca_topic_score_gemma":0.0006981062,"domain_scores_codex":[0.9998678,0.00003739519,0.000007373598,0.00001586135,0.00003946398,0.00003210351],"domain_scores_gemma":[0.9998791,0.00004122999,0.00002349529,0.000007352952,0.00002038733,0.00002847085],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007775718,0.00001133513,0.0000716567,0.00001629804,0.000003212478,0.00001669809,0.00001234373,0.00009659518,0.9989859,0.00005363058,0.00001332642,0.0006412364],"study_design_scores_gemma":[0.000005455566,0.0002322413,0.002961307,0.000002876711,0.00001210194,0.0000730855,0.00001165549,0.0006478269,0.9956327,0.00001419804,0.000403306,0.000003259286],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997353,0.0003765296,0.00106859,0.00001280885,0.000006579434,0.000007243772,0.00005085519,0.00001817967,0.001106211],"genre_scores_gemma":[0.996956,0.0003206326,0.001212485,0.00002071545,0.000003633143,0.00001573357,0.0001775734,0.00001136719,0.001281852],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001160415,"threshold_uncertainty_score":0.003881991,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03202106478155293,"score_gpt":0.3141639690483325,"score_spread":0.2821429042667796,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}