{"id":"W2904974029","doi":"10.1021/acs.bioconjchem.8b00731","title":"Comparative Antigenicity of Thiourea and Adipic Amide Linked Neoglycoconjugates Containing Modified Oligomannose Epitopes for the Carbohydrate-Specific anti-HIV Antibody 2G12","year":2018,"lang":"en","type":"article","venue":"Bioconjugate Chemistry","topic":"Glycosylation and Glycoproteins Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University","funders":"National Institute of Allergy and Infectious Diseases; Canadian Institutes of Health Research; Austrian Science Fund; Government of Canada; National Institutes of Health; Michael Smith Health Research BC","keywords":"Chemistry; Epitope; Glycan; Stereochemistry; Bovine serum albumin; Biochemistry; Antibody; Glycoprotein","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003978493,0.0003264126,0.0004317757,0.00004392987,0.0003487112,0.00008942906,0.0004286315,0.0002830493,0.0000426289],"category_scores_gemma":[0.0001327284,0.000257656,0.0001498609,0.000169206,0.0009336499,0.00001422625,0.0002122473,0.0001878627,0.000008231843],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001644245,"about_ca_system_score_gemma":0.0001231924,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006571909,"about_ca_topic_score_gemma":0.00001562743,"domain_scores_codex":[0.998167,0.00006577487,0.0004676117,0.000613121,0.0002146069,0.0004718925],"domain_scores_gemma":[0.9983525,0.0001144135,0.0002412369,0.000627137,0.0005080382,0.0001566802],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005032046,0.00006131797,0.001375404,0.00009701859,0.0001699903,0.000002197103,0.0002992062,0.0000405982,0.996487,0.0001768927,0.000516808,0.0002703602],"study_design_scores_gemma":[0.001445671,0.0002739608,0.00305804,0.00004835486,0.0000329512,0.00001123474,0.0005295383,0.002143863,0.9768619,0.00009902156,0.0151874,0.0003080759],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932473,0.002353994,0.001523803,0.0002476934,0.0001013918,0.0009252154,0.0001591505,0.00002787456,0.001413535],"genre_scores_gemma":[0.9973705,0.0006831251,0.0004057025,0.00009845775,0.000534508,0.00009306866,0.0003305799,0.00003331769,0.0004506809],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01962511,"threshold_uncertainty_score":0.9999875,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03202106478155293,"score_gpt":0.3141639690483325,"score_spread":0.2821429042667796,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}