{"id":"W2905045032","doi":"10.1002/glia.23576","title":"miR‐223 promotes regenerative myeloid cell phenotype and function in the demyelinated central nervous system","year":2018,"lang":"en","type":"article","venue":"Glia","topic":"Neuroinflammation and Neurodegeneration Mechanisms","field":"Neuroscience","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"Natural Sciences and Engineering Research Council of Canada; Multiple Sclerosis Society of Canada","keywords":"Remyelination; Neuroinflammation; Microglia; Biology; Multiple sclerosis; Neuroscience; Central nervous system; Myelin; Phenotype; Immunology; Myeloid; Cell biology; Downregulation and upregulation; Inflammation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001324291,0.0001846889,0.0002601788,0.0001860075,0.0002170058,0.0004162498,0.00008542442,0.0001585706,0.0007366528],"category_scores_gemma":[0.0001284535,0.0001073341,0.0002243325,0.0001041477,0.0002214673,0.000113921,0.0001647932,0.0004181437,0.0004226378],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001945616,"about_ca_system_score_gemma":0.0002835742,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003760633,"about_ca_topic_score_gemma":0.0006614645,"domain_scores_codex":[0.9998815,0.00002110857,0.00001531497,0.00001453781,0.00003511142,0.00003246198],"domain_scores_gemma":[0.9999186,0.000011232,0.00002166062,0.000009652703,0.00001396553,0.00002493731],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000198553,0.00002717914,0.0002324576,0.00003395786,0.000004921175,0.00007553837,0.00002784554,0.00004690959,0.9975471,0.0001428352,0.00006186542,0.001600889],"study_design_scores_gemma":[0.00001911988,0.000319742,0.008595889,0.00001030834,0.00004516243,0.0005077224,0.00008141162,0.0007628553,0.9847409,0.0001441522,0.004766375,0.000006287929],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9943243,0.00128976,0.00167478,0.00009809084,0.0000321528,0.00001703065,0.0001660042,0.0001193282,0.002278507],"genre_scores_gemma":[0.9970706,0.000569167,0.001055506,0.00004323452,0.000007416147,0.00001328681,0.0001282273,0.00002606549,0.001086678],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007366528,"threshold_uncertainty_score":0.002464354,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02251719474236706,"score_gpt":0.2285225318004113,"score_spread":0.2060053370580442,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}