{"id":"W2905217039","doi":"10.1002/hed.25563","title":"Plasma circulating tumor DNA as a potential tool for disease monitoring in head and neck cancer","year":2018,"lang":"en","type":"article","venue":"Head & Neck","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Institute for Cancer Research","funders":"Wallenberg Centre for Molecular and Translational Medicine; National Center for Advancing Translational Sciences; Clinical and Translational Science Institute, Boston University; Cancerfonden; Barncancerfonden; National Cancer Institute; National Institutes of Health; Vetenskapsrådet; Göteborgs Universitet; Knut och Alice Wallenbergs Stiftelse","keywords":"Head and neck cancer; Medicine; Cancer; Head and neck squamous-cell carcinoma; Biomarker; Internal medicine; Oncology; Perioperative; Disease; Pathology; Surgery; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00103366,0.0002622013,0.0003639011,0.0008731015,0.0001832718,0.0006400601,0.0004069025,0.0004454629,0.00116402],"category_scores_gemma":[0.002680226,0.00013757,0.0001080009,0.0005823358,0.0003590991,0.0003945901,0.0002275832,0.0004656108,0.0002715952],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003328501,"about_ca_system_score_gemma":0.0004069321,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005376883,"about_ca_topic_score_gemma":0.0007575629,"domain_scores_codex":[0.9995674,0.0001894699,0.00003077928,0.00007421873,0.0001086333,0.00002944659],"domain_scores_gemma":[0.9985543,0.0006781919,0.0003893056,0.00005882122,0.0002109661,0.0001085588],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002390092,0.0002192855,0.666658,0.0005340916,0.00008451426,0.001169299,0.0004999639,0.001186248,0.07833082,0.0005813687,0.001708223,0.246638],"study_design_scores_gemma":[0.0003255417,0.00766707,0.7521535,0.000575008,0.0005903839,0.0181069,0.001302151,0.01630771,0.1718652,0.003695803,0.02729143,0.0001193017],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.961336,0.01903836,0.01400037,0.0008219805,0.00015074,0.0001451237,0.0009290276,0.0002280658,0.003350357],"genre_scores_gemma":[0.9865166,0.001725139,0.01062877,0.0001872404,0.00007828869,0.00006807544,0.0002785886,0.00001205325,0.0005052438],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00116402,"threshold_uncertainty_score":0.00546658,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01357172493521479,"score_gpt":0.2900508910742535,"score_spread":0.2764791661390387,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}