{"id":"W2905217039","doi":"10.1002/hed.25563","title":"Plasma circulating tumor DNA as a potential tool for disease monitoring in head and neck cancer","year":2018,"lang":"en","type":"article","venue":"Head & Neck","topic":"Cancer Genomics and Diagnostics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":41,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Institute for Cancer Research","funders":"Wallenberg Centre for Molecular and Translational Medicine; National Center for Advancing Translational Sciences; Clinical and Translational Science Institute, Boston University; Cancerfonden; Barncancerfonden; National Cancer Institute; National Institutes of Health; Vetenskapsrådet; Göteborgs Universitet; Knut och Alice Wallenbergs Stiftelse","keywords":"Head and neck cancer; Medicine; Cancer; Head and neck squamous-cell carcinoma; Biomarker; Internal medicine; Oncology; Perioperative; Disease; Pathology; Surgery; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005946523,0.0001372231,0.0001334529,0.00003042387,0.0001013227,0.00004757915,0.00007833087,0.00006063029,0.00001131053],"category_scores_gemma":[0.0001131578,0.0001504354,0.00005667522,0.00004947799,0.00005260804,0.000004973424,0.00008725048,0.00005238742,0.000004420824],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003701942,"about_ca_system_score_gemma":0.0001770907,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003338938,"about_ca_topic_score_gemma":0.0003672562,"domain_scores_codex":[0.9990859,0.00001095111,0.000182642,0.0003498399,0.00007436942,0.0002963089],"domain_scores_gemma":[0.999546,0.0000166026,0.00005240456,0.0001935581,0.00006472327,0.0001267373],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001749019,0.0002023471,0.3467343,0.0002614663,0.00007901817,0.00008255165,0.0002817799,0.0006513313,0.6183973,0.0002133355,0.001691637,0.02965594],"study_design_scores_gemma":[0.01051484,0.001832164,0.6619888,0.0007392307,0.0001558087,0.00007776156,0.0001900858,0.01196885,0.2304702,0.001254911,0.07929157,0.001515769],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9976137,0.001146968,0.0001120894,0.0001778407,0.0004505192,0.0003009913,0.00007508024,0.000008267704,0.0001144871],"genre_scores_gemma":[0.9970327,0.000180349,0.0006845511,0.0002687753,0.001555868,0.0001129752,0.00002920557,0.00002892786,0.0001066659],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3879271,"threshold_uncertainty_score":0.6134578,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01357172493521479,"score_gpt":0.2900508910742535,"score_spread":0.2764791661390387,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}