{"id":"W2905238014","doi":"10.1016/j.jid.2018.11.030","title":"Relationship of Chromosome Arm 10q Variants to Occurrence of Multiple Primary Melanoma in the Population-Based Genes, Environment, and Melanoma (GEM) Study","year":2018,"lang":"en","type":"letter","venue":"Journal of Investigative Dermatology","topic":"Cutaneous Melanoma Detection and Management","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia","funders":"National Institute of Environmental Health Sciences; National Institute of General Medical Sciences; National Cancer Institute","keywords":"Genetics; Pedigree chart; CDKN2A; Melanoma; Single-nucleotide polymorphism; Genome-wide association study; BAP1; Biology; Population; Linkage disequilibrium; Genetic association; Hum; Gene; Medicine; Genotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003720483,0.0002478855,0.000321265,0.0004625405,0.0006581518,0.0005661027,0.0003446442,0.001288843,0.002950833],"category_scores_gemma":[0.002208168,0.0002969616,0.0003618128,0.00058149,0.0002445047,0.0003561316,0.0002827446,0.001227926,0.0002606192],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002025512,"about_ca_system_score_gemma":0.0002808277,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003165612,"about_ca_topic_score_gemma":0.003659461,"domain_scores_codex":[0.9997029,0.00009585309,0.0000294715,0.00009122131,0.00004057286,0.00004004273],"domain_scores_gemma":[0.998869,0.0004683874,0.0002042521,0.00009711033,0.000127988,0.0002332741],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0003029609,0.00008800679,0.9824181,0.0000117293,0.0001373846,0.01097996,0.0002050728,0.00007877314,0.001598613,0.0001049716,0.001254842,0.002819609],"study_design_scores_gemma":[0.00005189082,0.0002737853,0.962451,0.00002108618,0.0001973548,0.03346179,0.0005986574,0.0006998757,0.0003383747,0.0002317047,0.001656817,0.00001763682],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9934204,0.0003090579,0.0001872387,0.003189584,0.0001004215,0.000008620616,0.0003618533,0.00001159201,0.002411124],"genre_scores_gemma":[0.9984491,0.0001219863,0.0001191821,0.000531916,0.0001203276,0.000004454874,0.00007114745,0.000003364043,0.0005784305],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003165612,"threshold_uncertainty_score":0.009871542,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03691376271400834,"score_gpt":0.2648199453018788,"score_spread":0.2279061825878705,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}