{"id":"W2905343669","doi":"10.1002/em.22248","title":"Understanding the importance of low‐molecular weight (ethylene oxide‐ and propylene oxide‐induced) DNA adducts and mutations in risk assessment: Insights from 15 years of research and collaborative discussions","year":2018,"lang":"en","type":"review","venue":"Environmental and Molecular Mutagenesis","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Sherbrooke","funders":"European Chemical Industry Council","keywords":"Mutagenesis; Adduct; DNA adduct; Computational biology; Mutagen; Risk assessment; DNA damage; Chemistry; Toxicology; Mutation; DNA; Genetics; Biology; Gene; Computer science; Organic chemistry; Computer security","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01404124,0.0009518557,0.002169211,0.003473402,0.0006039007,0.003942771,0.001264283,0.002272731,0.001247352],"category_scores_gemma":[0.007994213,0.0004844534,0.0009406615,0.00241247,0.004258061,0.007496866,0.002593989,0.00448499,0.0004221399],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002073723,"about_ca_system_score_gemma":0.002899933,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001905099,"about_ca_topic_score_gemma":0.002509552,"domain_scores_codex":[0.9962527,0.001449906,0.0003560939,0.0007100018,0.00109011,0.0001412691],"domain_scores_gemma":[0.9844727,0.01186465,0.001013657,0.0004226611,0.001994158,0.000232273],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002473297,0.0001208169,0.003602965,0.01995108,0.0003391233,0.0007024148,0.003258253,0.003104774,0.02221265,0.07030516,0.00550362,0.8706518],"study_design_scores_gemma":[0.00002243883,0.0007993525,0.01219605,0.01558449,0.0005052467,0.001997981,0.005829542,0.00255488,0.01946961,0.1956797,0.745043,0.0003176996],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.004605004,0.9722425,0.01109605,0.008824799,0.0004348632,0.00002706181,0.00006527849,0.00002494704,0.002679489],"genre_scores_gemma":[0.026756,0.9576097,0.01069168,0.002949912,0.000634804,0.00004302976,0.0001083473,0.00002008727,0.00118648],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01404124,"threshold_uncertainty_score":0.07425803,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03651003560972554,"score_gpt":0.3165829674747882,"score_spread":0.2800729318650627,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}