{"id":"W2905385734","doi":"10.1007/978-1-4939-8958-4_4","title":"Monoclonal Antibodies for the Treatment of Melanoma: Present and Future Strategies","year":2018,"lang":"en","type":"review","venue":"Methods in molecular biology","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":67,"is_retracted":false,"has_abstract":false,"ca_institutions":"Quest University Canada; University of British Columbia","funders":"","keywords":"Ipilimumab; Nivolumab; Monoclonal antibody; Pembrolizumab; Medicine; Melanoma; Antibody; Adverse effect; Immunotherapy; TIGIT; Immunology; Monoclonal; Oncology; Immune system; Internal medicine; Cancer research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000932192,0.0003197628,0.001654691,0.0002039321,0.00003774098,0.00001189389,0.0001752813,0.0004256008,0.0001017563],"category_scores_gemma":[0.00005608961,0.0001656523,0.00045411,0.0001677884,0.0005511791,0.000007803137,0.00006527281,0.0001832174,7.573992e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007720322,"about_ca_system_score_gemma":0.0002666985,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004714926,"about_ca_topic_score_gemma":0.000006012416,"domain_scores_codex":[0.997555,0.001185436,0.0004456085,0.000425932,0.00008598671,0.000302091],"domain_scores_gemma":[0.9979159,0.001265079,0.0001593394,0.0005274661,0.00008404526,0.00004814518],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001092415,0.000102944,0.00001315277,0.002744962,0.0008194027,0.00001676026,0.0001455003,1.039319e-7,0.002262999,0.0009988856,0.00003405489,0.992752],"study_design_scores_gemma":[0.000631251,0.001988083,0.00001191681,0.0003449723,0.0006313428,0.00007581426,0.00009049881,0.00001794716,0.001339547,0.001330526,0.9934133,0.0001248033],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0000407449,0.9685525,0.02829847,0.0002276965,0.0002222536,0.002246066,0.00004729083,0.000008057514,0.0003568847],"genre_scores_gemma":[1.934896e-7,0.8040353,0.1945126,0.00001096265,0.0006240241,0.0003790931,0.0000601999,0.00003134421,0.0003463159],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9933792,"threshold_uncertainty_score":0.6755105,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1160249317433525,"score_gpt":0.5236938188093235,"score_spread":0.407668887065971,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}