{"id":"W2905385734","doi":"10.1007/978-1-4939-8958-4_4","title":"Monoclonal Antibodies for the Treatment of Melanoma: Present and Future Strategies","year":2018,"lang":"en","type":"review","venue":"Methods in molecular biology","topic":"CAR-T cell therapy research","field":"Medicine","cited_by":67,"is_retracted":false,"has_abstract":false,"ca_institutions":"Quest University Canada; University of British Columbia","funders":"","keywords":"Ipilimumab; Nivolumab; Monoclonal antibody; Pembrolizumab; Medicine; Melanoma; Antibody; Adverse effect; Immunotherapy; TIGIT; Immunology; Monoclonal; Oncology; Immune system; Internal medicine; Cancer research","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007594932,0.0007977001,0.001109697,0.001552319,0.0001946576,0.0009400563,0.0008979894,0.001135638,0.003412219],"category_scores_gemma":[0.0007416646,0.0002504908,0.00045033,0.001075971,0.0005663,0.001495686,0.0006386184,0.002594426,0.001550126],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005087575,"about_ca_system_score_gemma":0.0008264076,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006988981,"about_ca_topic_score_gemma":0.001732216,"domain_scores_codex":[0.9998447,0.00002760937,0.00001698003,0.00002675109,0.0000616804,0.00002241079],"domain_scores_gemma":[0.9996533,0.0001864791,0.00004251424,0.000009156914,0.00007191694,0.00003666704],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001204805,0.0001063097,0.0001266328,0.008726007,0.00007541974,0.0001531106,0.00003748235,0.0003575764,0.002861333,0.005815702,0.03383013,0.9477898],"study_design_scores_gemma":[0.00004802328,0.0001306882,0.0003910494,0.001805304,0.00011894,0.0007551092,0.00003095882,0.0001429966,0.0007172733,0.002831056,0.9930114,0.00001716024],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00008978097,0.998638,0.0001689217,0.0003779046,0.0002218423,0.000003261685,0.00001025655,0.000006631582,0.0004834304],"genre_scores_gemma":[0.0007190443,0.9979094,0.0002249971,0.0003316102,0.0002975098,0.000005833943,0.00001941777,0.000001422212,0.0004906838],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003412219,"threshold_uncertainty_score":0.011415,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1160249317433525,"score_gpt":0.5236938188093235,"score_spread":0.407668887065971,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}