{"id":"W2905435570","doi":"10.1016/j.tem.2018.11.003","title":"Sphingolipids in the Pathogenesis of Parkinson’s Disease and Parkinsonism","year":2018,"lang":"en","type":"review","venue":"Trends in Endocrinology and Metabolism","topic":"Lysosomal Storage Disorders Research","field":"Medicine","cited_by":131,"is_retracted":false,"has_abstract":false,"ca_institutions":"","funders":"Parkinson Canada; Howard Hughes Medical Institute","keywords":"Sphingolipid; Pathogenesis; Parkinsonism; Disease; Neuroscience; Parkinson's disease; Medicine; Biology; Pathology; Cell biology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006217891,0.0007972008,0.001269861,0.00241312,0.0002729037,0.001329788,0.000793018,0.001207847,0.002904186],"category_scores_gemma":[0.0008281888,0.0002207153,0.000430417,0.002275619,0.0005693538,0.001439129,0.0009540179,0.001532206,0.001328488],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005851324,"about_ca_system_score_gemma":0.001445509,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001403168,"about_ca_topic_score_gemma":0.002349853,"domain_scores_codex":[0.9998127,0.00002814587,0.00003887521,0.00002523827,0.00007553388,0.00001949927],"domain_scores_gemma":[0.999632,0.000141897,0.00007191191,0.000009269692,0.0001019665,0.0000429386],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001475818,0.00007109583,0.0004546522,0.01516737,0.00015836,0.0005098984,0.00008545742,0.0002706324,0.001682447,0.004696193,0.02783256,0.9489237],"study_design_scores_gemma":[0.00004073968,0.0000781862,0.001422286,0.005445768,0.0002031753,0.002726798,0.0001201136,0.0001008086,0.0004264657,0.004059657,0.9853501,0.00002588599],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006654362,0.9992317,0.00003682662,0.0002015543,0.0001161553,0.000001460566,0.000007724861,0.000002337332,0.0003356565],"genre_scores_gemma":[0.0004520215,0.9989659,0.00006344534,0.00008260529,0.0001948464,0.000001686458,0.00001358171,3.905709e-7,0.0002255736],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002904186,"threshold_uncertainty_score":0.009715438,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0622696773793338,"score_gpt":0.3662787824278346,"score_spread":0.3040091050485008,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}