{"id":"W2905634767","doi":"10.1183/13993003.congress-2018.pa1265","title":"Contribution of the Saguenay–Lac-Saint-Jean asthma familial cohort in the omic landscape of asthma","year":2018,"lang":"en","type":"article","venue":"Genes and Environment","topic":"IL-33, ST2, and ILC Pathways","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Chicoutimi","funders":"","keywords":"Asthma; Epigenomics; Cohort; Expression quantitative trait loci; Medicine; Biology; Bioinformatics; Genetics; Immunology; Gene; Single-nucleotide polymorphism; DNA methylation; Internal medicine; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003391005,0.0001060264,0.000184051,0.00002437157,0.0001095893,0.000002962006,0.0001560719,0.0001175591,0.00008953321],"category_scores_gemma":[0.00001740334,0.00006096896,0.00005654929,0.00004411307,0.000382266,0.00002023509,0.0000877808,0.00009308278,0.0000425794],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001886791,"about_ca_system_score_gemma":0.0000110624,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005514529,"about_ca_topic_score_gemma":0.0002184342,"domain_scores_codex":[0.9992127,0.0001575955,0.0002253758,0.0001620738,0.0000483425,0.000193891],"domain_scores_gemma":[0.9995776,0.00004634936,0.0001015147,0.0002541095,0.0000115686,0.000008847629],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0003050623,0.0002560208,0.2798726,0.00002613486,0.0001386886,0.000001691943,0.002024333,0.00008281329,0.7001835,0.001192783,0.00148994,0.01442652],"study_design_scores_gemma":[0.00119045,0.00039355,0.7450858,0.00002022267,0.00002876276,0.00001870283,0.000511036,0.00003124664,0.1206675,0.0001424648,0.1318,0.0001102725],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997314,0.001469349,0.00007041737,0.000301032,0.0002418659,0.0002376079,0.0001549517,0.000003569422,0.0002071479],"genre_scores_gemma":[0.9985954,0.0009946864,0.000007430261,0.00010208,0.00005320494,0.00001091725,0.00004066962,0.000005105113,0.0001905124],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.579516,"threshold_uncertainty_score":0.2486242,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005822009813953808,"score_gpt":0.182707376368396,"score_spread":0.1768853665544422,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}