{"id":"W2906031711","doi":"10.3389/fncel.2018.00499","title":"New Therapeutic Avenues of mCSF for Brain Diseases and Injuries","year":2018,"lang":"en","type":"article","venue":"Frontiers in Cellular Neuroscience","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre hospitalier universitaire de Québec; Université Laval","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research","keywords":"Microglia; Chemokine; Inflammation; Cell biology; Immune system; Proinflammatory cytokine; Macrophage colony-stimulating factor; CCL2; Macrophage; Neuroscience; Myelin; Immunology; Biology; Chemistry; Central nervous system; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001528492,0.0001075195,0.0001962209,0.0001094439,0.0001122036,0.00001287542,0.0002928587,0.00007472959,0.00002014473],"category_scores_gemma":[0.0001525045,0.000101668,0.00003928192,0.0001770598,0.001148719,0.00009440595,0.00007976074,0.00008787864,0.000003540834],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001644711,"about_ca_system_score_gemma":0.00008357039,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000149205,"about_ca_topic_score_gemma":0.000002215445,"domain_scores_codex":[0.9991441,0.00007810345,0.0001802962,0.0002979803,0.00003563559,0.0002638194],"domain_scores_gemma":[0.9995531,0.00008334132,0.00008607782,0.0002297403,0.00002886824,0.00001884369],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001477785,0.00003548927,0.02368552,0.00003122066,0.000007354931,9.781614e-7,0.0005599991,0.000001773894,0.92916,0.0003442795,0.01975795,0.02626766],"study_design_scores_gemma":[0.0009595802,0.0005062912,0.02993538,0.00004093736,0.00002521503,0.000004066726,0.0001319385,0.00008703854,0.7876123,0.005035877,0.1754609,0.0002005052],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7444679,0.05948024,0.1734223,0.001170308,0.01993581,0.0009877905,0.0001101968,0.00007621416,0.0003492582],"genre_scores_gemma":[0.9945391,0.000142993,0.001579498,0.0004941099,0.00004825485,0.00001190599,0.000004494337,0.00001389797,0.003165769],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2500712,"threshold_uncertainty_score":0.4232504,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01130386548564078,"score_gpt":0.2469398037198952,"score_spread":0.2356359382342545,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}