{"id":"W2906149031","doi":"10.1016/j.clinbiochem.2018.12.008","title":"An unusual case of alpha-1-antitrypsin deficiency: SZ/Z","year":2018,"lang":"eo","type":"article","venue":"Clinical Biochemistry","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of British Columbia; Providence Health Care; University of Toronto","funders":"","keywords":"Alpha 1-antitrypsin deficiency; Allele; Genotype; Genetics; Gene; Medicine; Disease; Immunology; Internal medicine; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003487949,0.002855365,0.001570836,0.003071603,0.002343823,0.001702238,0.001923123,0.004756866,0.002995373],"category_scores_gemma":[0.003804051,0.001218778,0.00118583,0.002174776,0.002890583,0.00183024,0.002221432,0.002479883,0.0008077329],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001049287,"about_ca_system_score_gemma":0.0007606416,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002054151,"about_ca_topic_score_gemma":0.001207759,"domain_scores_codex":[0.9994197,0.00005365182,0.00006020684,0.0001476646,0.00007607396,0.0002426632],"domain_scores_gemma":[0.9984998,0.000478192,0.0002869557,0.0001262601,0.00009603465,0.000512817],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.00005836897,0.00002083098,0.002545585,0.00001394104,0.000006676293,0.9957469,0.00006231521,0.0000362359,0.0006455794,0.0002976884,0.0001392119,0.0004268222],"study_design_scores_gemma":[0.0000320505,0.0000570691,0.004204381,0.000003409037,0.00001301719,0.9945827,0.00007029104,0.0001860685,0.0003316847,0.0002816137,0.0002282707,0.000009294727],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9794096,0.001539369,0.003594186,0.002864242,0.0003497176,0.0001543651,0.0003748281,0.0002227131,0.01149107],"genre_scores_gemma":[0.9953613,0.0004963311,0.001343105,0.0006087074,0.0004938825,0.00002496158,0.0001085159,0.00004017145,0.001523019],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004756866,"threshold_uncertainty_score":0.01002049,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02711768014733613,"score_gpt":0.378406919407647,"score_spread":0.3512892392603109,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}