{"id":"W2906212992","doi":"10.1002/cam4.1923","title":"LRP8 is overexpressed in estrogen‐negative breast cancers and a potential target for these tumors","year":2018,"lang":"en","type":"article","venue":"Cancer Medicine","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institut de Recherches Servier; BC Cancer Agency; Servier; Institut Curie; Université de Recherche Paris Sciences et Lettres; Centre National de la Recherche Scientifique; Institut National de la Santé et de la Recherche Médicale; Cancer Research UK","keywords":"Breast cancer; Cancer research; Estrogen receptor; Triple-negative breast cancer; Estrogen; LDL receptor; Medicine; Internal medicine; Cancer; Lipoprotein; Cholesterol","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009487019,0.0002289184,0.0002583973,0.0001687924,0.0001218919,0.0002105018,0.0001217744,0.0002144491,0.0009303857],"category_scores_gemma":[0.00009944674,0.0001039768,0.0001716565,0.0001435934,0.0001114022,0.0001670607,0.0001252503,0.0003591697,0.0003400944],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001710545,"about_ca_system_score_gemma":0.0001217192,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001625917,"about_ca_topic_score_gemma":0.0002369803,"domain_scores_codex":[0.9999417,0.000008341292,0.000004495377,0.0000142146,0.00001832869,0.0000128489],"domain_scores_gemma":[0.999962,0.00000598615,0.00001387785,0.000003403222,0.000006046608,0.000008772051],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001874647,0.00001976656,0.001447214,0.0001035404,0.00001078628,0.0002596454,0.000009831057,0.00004788194,0.9906592,0.00006830448,0.0001736367,0.00701286],"study_design_scores_gemma":[0.00007199041,0.0008421595,0.07968371,0.00003277262,0.00009377535,0.006213942,0.0001200516,0.00166055,0.8891429,0.0003141151,0.02181032,0.00001370616],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9787209,0.01513615,0.002873748,0.000506774,0.00005908464,0.00003528829,0.0007195406,0.0001146143,0.001833956],"genre_scores_gemma":[0.9876378,0.005968997,0.002704089,0.0001227041,0.0000284059,0.00004678556,0.001234668,0.00001374387,0.002242811],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009303857,"threshold_uncertainty_score":0.003112495,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00869983721301431,"score_gpt":0.2715447335007359,"score_spread":0.2628448962877216,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}