{"id":"W2906212992","doi":"10.1002/cam4.1923","title":"LRP8 is overexpressed in estrogen‐negative breast cancers and a potential target for these tumors","year":2018,"lang":"en","type":"article","venue":"Cancer Medicine","topic":"Protease and Inhibitor Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institut de Recherches Servier; BC Cancer Agency; Servier; Institut Curie; Université de Recherche Paris Sciences et Lettres; Centre National de la Recherche Scientifique; Institut National de la Santé et de la Recherche Médicale; Cancer Research UK","keywords":"Breast cancer; Cancer research; Estrogen receptor; Triple-negative breast cancer; Estrogen; LDL receptor; Medicine; Internal medicine; Cancer; Lipoprotein; Cholesterol","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000105745,0.0001353642,0.0001701179,0.00003662641,0.00004377061,0.000005178368,0.00009143847,0.00008219632,0.0001314428],"category_scores_gemma":[0.00004561618,0.0001094169,0.00003140618,0.00006554589,0.0002068411,0.000005014509,0.00004164127,0.00005603968,0.000001009148],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003905828,"about_ca_system_score_gemma":0.0001577467,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005869472,"about_ca_topic_score_gemma":0.00008183327,"domain_scores_codex":[0.9991906,0.00002024968,0.0001479848,0.0003141163,0.00009670122,0.0002303205],"domain_scores_gemma":[0.999576,0.000006591728,0.00006561697,0.0001593298,0.00009456754,0.00009786815],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004955461,0.0000147342,0.0004489716,0.00003412862,0.00004549141,0.000003105437,0.000448131,0.000004670875,0.986889,0.0001057854,0.009785027,0.00172541],"study_design_scores_gemma":[0.002572912,0.0009499071,0.0004655274,0.0001884952,0.0000244787,0.00001741627,0.0002518992,0.0002618376,0.984585,0.00127578,0.009237756,0.0001690211],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9933733,0.002412698,0.001350613,0.001313489,0.000346674,0.0005463574,0.0002541092,0.000009230862,0.000393507],"genre_scores_gemma":[0.9960412,0.0002083786,0.0003540675,0.001358651,0.001612299,0.0001752063,0.00003375347,0.00001865962,0.0001977437],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002667919,"threshold_uncertainty_score":0.4461892,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00869983721301431,"score_gpt":0.2715447335007359,"score_spread":0.2628448962877216,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}