{"id":"W2906220413","doi":"10.3389/fgene.2018.00720","title":"Interaction of the Host and Viral Genome and Their Influence on HIV Disease","year":2019,"lang":"en","type":"review","venue":"Frontiers in Genetics","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":40,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; Public Health Agency of Canada","funders":"","keywords":"Biology; Human leukocyte antigen; Genetic variation; Genotyping; Genetics; Viral load; Virus; Disease; Immune system; Viral evolution; Genome-wide association study; Genotype; Virology; Immunology; Genome; Gene; Antigen; Single-nucleotide polymorphism; Medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006285043,0.0001794772,0.0004774928,0.0001072177,0.00004139619,0.000008669597,0.0001584422,0.000149837,0.000008566823],"category_scores_gemma":[0.00002904567,0.0001028878,0.00008132309,0.0000611243,0.0002201381,0.00001623851,0.0001332268,0.0002889086,0.00003280543],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000552498,"about_ca_system_score_gemma":0.00009669819,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000004854648,"about_ca_topic_score_gemma":0.000002041274,"domain_scores_codex":[0.9991778,0.0002094208,0.0001983488,0.0002207802,0.00002334806,0.0001703272],"domain_scores_gemma":[0.9994982,0.00006135464,0.0001094469,0.0002915891,0.00001474705,0.00002469549],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001314575,0.0001459463,0.01312202,0.003768879,0.0005401134,0.000005665765,0.0003262396,0.000009975927,0.0001693466,0.00002041795,0.001119524,0.9806404],"study_design_scores_gemma":[0.0003881088,0.0001344178,0.01080811,0.001497761,0.000149,0.000007900897,0.00004736463,0.000002252715,0.00003942349,0.00003041057,0.9867683,0.0001269434],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01470538,0.9838474,0.0000123683,0.00001809215,0.0003665729,0.0005727417,0.0004103594,0.000003072982,0.00006399649],"genre_scores_gemma":[0.007262039,0.992008,0.00003483907,0.00001396152,0.000009289846,0.00002714054,0.0001066933,0.00001247768,0.0005255778],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9856488,"threshold_uncertainty_score":0.4195643,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01811989654673203,"score_gpt":0.2781261058393138,"score_spread":0.2600062092925818,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}