{"id":"W2906835339","doi":"10.1002/pros.23754","title":"CUL4B/miR‐33b/C‐MYC axis promotes prostate cancer progression","year":2019,"lang":"en","type":"article","venue":"The Prostate","topic":"Ubiquitin and proteasome pathways","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"Public Health Ontario; University of Toronto","funders":"National Natural Science Foundation of China","keywords":"Gene silencing; Cullin; Cancer research; Ubiquitin ligase; Prostate cancer; microRNA; Epigenetics; Biology; Cancer; Chromatin immunoprecipitation; DU145; Molecular biology; Ubiquitin; Gene expression; LNCaP; Promoter; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001739005,0.000403281,0.0002799923,0.0004698585,0.0003101368,0.0005533561,0.0002089863,0.0002360575,0.003023885],"category_scores_gemma":[0.0001524334,0.00023043,0.0004243701,0.0002672962,0.0002470823,0.0001574738,0.0003826024,0.0006546592,0.0007027006],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006602162,"about_ca_system_score_gemma":0.0006179655,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001722876,"about_ca_topic_score_gemma":0.001666004,"domain_scores_codex":[0.9998239,0.00002128406,0.000008062118,0.00004251107,0.00005346176,0.0000506933],"domain_scores_gemma":[0.9998708,0.000009626557,0.00004564989,0.00000685387,0.00002069964,0.00004634291],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000801129,0.00008649503,0.009291291,0.0004969136,0.0001073073,0.0004747515,0.00005938733,0.000794146,0.9733557,0.000779142,0.002021505,0.01173234],"study_design_scores_gemma":[0.0001334817,0.0005980418,0.1776537,0.00008155341,0.0003171686,0.00251226,0.0001940155,0.01533911,0.7606633,0.0007633006,0.041693,0.00005101564],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9508815,0.02344636,0.01137535,0.0007303499,0.000129664,0.000114705,0.00373405,0.001405939,0.008182134],"genre_scores_gemma":[0.9923576,0.002287996,0.001748416,0.00009582339,0.00001481851,0.00004419926,0.0009989428,0.00004146264,0.002410764],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003023885,"threshold_uncertainty_score":0.01011592,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009616945087548137,"score_gpt":0.2699397477535834,"score_spread":0.2603228026660352,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}