{"id":"W2906917595","doi":"10.1007/s40265-018-1032-1","title":"Immune Checkpoint Inhibitors in the Treatment of Gastroesophageal Cancer","year":2019,"lang":"en","type":"review","venue":"Drugs","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval","funders":"","keywords":"Nivolumab; Medicine; Pembrolizumab; Immune checkpoint; Blockade; Cancer; Oncology; Ipilimumab; Internal medicine; Atezolizumab; Immunotherapy; Microsatellite instability; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005659959,0.0008085311,0.001729828,0.001650639,0.0001895388,0.0008857307,0.0007581649,0.000944863,0.003749385],"category_scores_gemma":[0.0009439537,0.0002126987,0.0006482614,0.001495705,0.0002950809,0.0008203893,0.0005819463,0.002122398,0.001306375],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004892073,"about_ca_system_score_gemma":0.0008156231,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001068899,"about_ca_topic_score_gemma":0.003171502,"domain_scores_codex":[0.9998316,0.00003703672,0.00002938588,0.00002792023,0.00005530231,0.00001875589],"domain_scores_gemma":[0.9995998,0.0002251752,0.00007196503,0.000007697608,0.00006627592,0.00002916665],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001835901,0.00006271499,0.0001110111,0.02165981,0.0001859336,0.0000956201,0.00002214931,0.0003300502,0.0007376526,0.001699705,0.02702274,0.9478891],"study_design_scores_gemma":[0.0001546914,0.0003118311,0.001067821,0.011688,0.0007306911,0.0008485446,0.00004305135,0.0001901144,0.0003789474,0.001657403,0.9829043,0.000024779],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00005138833,0.9992167,0.00004375269,0.000170817,0.0001405917,0.000002926424,0.00001300731,0.000003440877,0.0003572995],"genre_scores_gemma":[0.0004901516,0.9986235,0.00009927437,0.0002714278,0.0001550298,0.000004882025,0.00002302371,7.728074e-7,0.000331844],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003749385,"threshold_uncertainty_score":0.0125429,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03974246553099459,"score_gpt":0.3481894594858245,"score_spread":0.3084469939548299,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}