{"id":"W2906945679","doi":"10.1167/iovs.18-24461","title":"Photoreceptor Progenitors Depend Upon Coordination of<i>gdf6a</i>,<i>thrβ</i>, and<i>tbx2b</i>to Generate Precise Populations of Cone Photoreceptor Subtypes","year":2018,"lang":"en","type":"article","venue":"Investigative Ophthalmology & Visual Science","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Zebrafish; Mutant; Biology; Phenotype; Gene knockdown; Retina; Cell biology; Retinal; Genetics; Gene; Biochemistry; Neuroscience","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005294788,0.0002186293,0.0002621076,0.0001876923,0.0002287452,0.00002217282,0.0003264883,0.0001391487,0.00007041186],"category_scores_gemma":[0.0006511934,0.0002040952,0.00005051233,0.0007153256,0.002442904,0.00003411381,0.0002276172,0.00007210817,0.00001141562],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002930588,"about_ca_system_score_gemma":0.0003754158,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001139649,"about_ca_topic_score_gemma":0.00003190523,"domain_scores_codex":[0.9982346,0.0001239825,0.0003929023,0.0005987071,0.0003078126,0.0003419812],"domain_scores_gemma":[0.9985982,0.0000287035,0.0002683314,0.0002019862,0.0006622092,0.0002405665],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001201777,0.00007252525,0.07827032,0.00001288653,0.00001759978,0.000001157744,0.0003934084,0.000006432041,0.9206243,0.00006922863,0.000151147,0.0002608864],"study_design_scores_gemma":[0.0003048199,0.001333427,0.03977197,0.00002633751,0.00001554066,0.00002100472,0.0001359391,0.00009411298,0.9573752,0.0003972611,0.0003057435,0.0002186131],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9983124,0.0001476331,0.00003201576,0.00009660526,0.0004028067,0.0005041808,0.00002549248,0.000009943365,0.0004689764],"genre_scores_gemma":[0.9937764,0.00001175182,0.005775158,0.0000719388,0.00009890382,0.00005381276,0.00004617912,0.00001648243,0.0001493382],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03849835,"threshold_uncertainty_score":0.9000982,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02723224710310367,"score_gpt":0.3199772076024708,"score_spread":0.2927449604993672,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}