{"id":"W2906945679","doi":"10.1167/iovs.18-24461","title":"Photoreceptor Progenitors Depend Upon Coordination of<i>gdf6a</i>,<i>thrβ</i>, and<i>tbx2b</i>to Generate Precise Populations of Cone Photoreceptor Subtypes","year":2018,"lang":"en","type":"article","venue":"Investigative Ophthalmology & Visual Science","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Zebrafish; Mutant; Biology; Phenotype; Gene knockdown; Retina; Cell biology; Retinal; Genetics; Gene; Biochemistry; Neuroscience","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000115848,0.0004715714,0.0002167372,0.0001876054,0.0001852761,0.0004239947,0.0003234899,0.0002387961,0.0007779711],"category_scores_gemma":[0.0001297395,0.0003602167,0.0002628514,0.0001072435,0.0003132734,0.0001815236,0.0004826868,0.000662046,0.0006191107],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00048649,"about_ca_system_score_gemma":0.0004017392,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001611735,"about_ca_topic_score_gemma":0.003183936,"domain_scores_codex":[0.9998037,0.0000105372,0.00002193771,0.00005030195,0.00007792213,0.00003556922],"domain_scores_gemma":[0.9998016,0.00001870969,0.0000807229,0.00002204771,0.00002112573,0.00005588361],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001973258,0.000004918423,0.0002780786,0.000009441142,0.000001308362,0.00001784936,0.000008394827,0.00003208343,0.9991089,0.00006690824,0.00001285733,0.0004395466],"study_design_scores_gemma":[0.000009046261,0.00004601274,0.005330603,0.000006784569,0.000009040146,0.000186425,0.00002127282,0.0004824871,0.9919353,0.00003071541,0.00193975,0.000002593966],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9896561,0.0007452461,0.005445883,0.000063128,0.00002040213,0.00003573987,0.0004356301,0.000168319,0.003429612],"genre_scores_gemma":[0.9853269,0.0006812637,0.007001334,0.00008694507,0.000008657857,0.00005916024,0.000702147,0.0001901193,0.005943513],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001611735,"threshold_uncertainty_score":0.003529787,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02723224710310367,"score_gpt":0.3199772076024708,"score_spread":0.2927449604993672,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}