{"id":"W2906993515","doi":"10.1039/c8ob02982b","title":"Enhancing T cell responses and tumour immunity by vaccination with peptides conjugated to a weak NKT cell agonist","year":2019,"lang":"en","type":"article","venue":"Organic & Biomolecular Chemistry","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institute of General Medical Sciences; Health Research Council of New Zealand; National Health and Medical Research Council; Ministry of Business, Innovation and Employment; Cancer Research Trust New Zealand","keywords":"Chemistry; Agonist; Conjugated system; Cell; Vaccination; Immunity; Immune system; Immunology; Cell biology; Receptor; Biochemistry; Biology; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001381276,0.0004740917,0.0002299562,0.0001424889,0.00009443569,0.0002463888,0.0001383056,0.000298629,0.001014032],"category_scores_gemma":[0.0001032374,0.0001139948,0.0002193923,0.0001130916,0.0002211929,0.0002429577,0.0002292976,0.0005272457,0.0003360936],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001703845,"about_ca_system_score_gemma":0.0001583693,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009963098,"about_ca_topic_score_gemma":0.0001540063,"domain_scores_codex":[0.9998708,0.00003174146,0.000009658393,0.00002591003,0.00002890528,0.00003291408],"domain_scores_gemma":[0.9999503,0.000009702691,0.000016083,0.000006467252,0.000005149003,0.0000123458],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000399635,0.00001976242,0.00003682119,0.00002264359,0.00000256629,0.00001350439,0.000004179307,0.00006054731,0.9987566,0.00005698378,0.000007536453,0.0009787417],"study_design_scores_gemma":[0.00001170936,0.0003650266,0.0002678514,0.000002722107,0.000008127863,0.0001120034,0.000003068352,0.0002578431,0.9980693,0.00002607562,0.0008747787,0.000001588715],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9882489,0.002109391,0.00757303,0.0000905285,0.00003663351,0.000065653,0.00005635433,0.00005376942,0.001765655],"genre_scores_gemma":[0.9930558,0.001084093,0.004256858,0.00005402095,0.00001986903,0.0000344029,0.0000936637,0.00001400152,0.001387259],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001014032,"threshold_uncertainty_score":0.00339222,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.002813411597821366,"score_gpt":0.1953900849177755,"score_spread":0.1925766733199542,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}