{"id":"W2907028960","doi":"10.1001/jamaoncol.2018.5904","title":"Association of Patient Sex With Efficacy of Immune Checkpoint Inhibitors and Overall Survival in Advanced Cancers","year":2019,"lang":"en","type":"review","venue":"JAMA Oncology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":302,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Medicine; Immunotherapy; Hazard ratio; Meta-analysis; Internal medicine; Randomized controlled trial; Observational study; Clinical trial; Oncology; MEDLINE; Cancer; Confidence interval","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01373159,0.001193998,0.0041422,0.002263214,0.0003800457,0.002347907,0.0009293389,0.001291016,0.001912852],"category_scores_gemma":[0.0341774,0.0005606653,0.02133084,0.003103914,0.0005904703,0.001233638,0.0006889169,0.001380956,0.0001260821],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007307342,"about_ca_system_score_gemma":0.0009922491,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001902206,"about_ca_topic_score_gemma":0.002794822,"domain_scores_codex":[0.9893222,0.005904243,0.002164868,0.001314517,0.001043072,0.0002511268],"domain_scores_gemma":[0.9662197,0.02655081,0.005135803,0.0009829531,0.0008325119,0.0002783164],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"systematic_review","study_design_scores_codex":[0.01032964,0.00007942844,0.1330615,0.06657441,0.7498436,0.0001592984,0.0001425954,0.001549068,0.0006453072,0.0003462024,0.0009882773,0.03628065],"study_design_scores_gemma":[0.001816264,0.001249979,0.1053205,0.01020165,0.8744922,0.0003877156,0.0001199623,0.001115569,0.0006291006,0.001289083,0.00332463,0.00005350303],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.07042504,0.9250405,0.001196488,0.0009076711,0.000396318,0.0001212489,0.0009167032,0.00002488037,0.0009709953],"genre_scores_gemma":[0.8224792,0.1723406,0.00188248,0.001143183,0.0007280034,0.000227186,0.0008060096,0.00003078546,0.0003626108],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.01373159,"threshold_uncertainty_score":0.07262045,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01836268428872953,"score_gpt":0.3204437840325803,"score_spread":0.3020810997438508,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}