{"id":"W2907108353","doi":"10.1142/s0218339018500262","title":"MODELING MONOCYTE-DERIVED DENDRITIC CELLS AS A THERAPEUTIC VACCINE AGAINST HIV","year":2018,"lang":"en","type":"article","venue":"Journal of Biological Systems","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Vaccination; Antigen presentation; Immunology; Immune system; Dendritic cell; Immunotherapy; Human immunodeficiency virus (HIV); Antigen; Monocyte; Cross-presentation; Virology; Virus; Interferon; Antigen-presenting cell; Secretion; Biology; T cell","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004965878,0.0001781417,0.0004837654,0.0001101118,0.0001743267,0.00003529487,0.0003010269,0.0002594735,0.0002693694],"category_scores_gemma":[0.00008040418,0.00009940283,0.0001815349,0.0001009374,0.000112564,0.00006321477,0.00005838487,0.0003315567,0.00240126],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009092091,"about_ca_system_score_gemma":0.00007494663,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004387378,"about_ca_topic_score_gemma":0.000003770639,"domain_scores_codex":[0.9982257,0.000486175,0.0005844901,0.0001903424,0.000070905,0.000442311],"domain_scores_gemma":[0.9991221,0.0001556564,0.0001917188,0.0001697717,0.0002701338,0.00009064995],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007162081,0.000286203,0.001522572,0.00001400486,0.0006136225,0.000142318,0.0001559553,0.0002057355,0.9921739,0.0001265429,0.0008787668,0.003164183],"study_design_scores_gemma":[0.03996735,0.0458142,0.007888366,0.001744064,0.0006708953,0.01040677,0.008416012,0.01079514,0.6918058,0.001933498,0.1780083,0.002549599],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.983807,0.0119087,0.002198171,0.0002194588,0.0008985811,0.0002305298,0.00001758416,0.00002618009,0.0006938424],"genre_scores_gemma":[0.9983912,0.0006732822,0.00005236574,0.000129398,0.0002789352,0.000008832656,0.00001469163,0.000009967148,0.0004413163],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3003681,"threshold_uncertainty_score":0.9983755,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0465949182560499,"score_gpt":0.2894606691410461,"score_spread":0.2428657508849962,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}