{"id":"W2907443362","doi":"10.1182/blood-2018-99-119302","title":"Results from Ongoing Phase 1/2 Clinical Trial of Tagraxofusp (SL-401) in Patients with Relapsed/Refractory Chronic Myelomonocytic Leukemia (CMML)","year":2018,"lang":"en","type":"article","venue":"Blood","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Medicine; Chronic myelomonocytic leukemia; Internal medicine; Refractory (planetary science); Interleukin-3 receptor; Regimen; Oncology; Decitabine; Azacitidine; Gastroenterology; Leukemia; Myelodysplastic syndromes; Bone marrow; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001256145,0.0003500622,0.0009936279,0.0002848066,0.00007363474,0.00002563364,0.000387449,0.0004112324,0.0001495958],"category_scores_gemma":[0.002273299,0.0002799277,0.0002029025,0.0005765472,0.0006713803,0.0001756106,0.0001960009,0.0007941538,0.000160119],"about_ca_system_candidate":true,"about_ca_system_consensus":true,"about_ca_system_score_codex":0.008117394,"about_ca_system_score_gemma":0.01622927,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001753594,"about_ca_topic_score_gemma":0.0005510647,"domain_scores_codex":[0.9952201,0.0002957762,0.001667473,0.0009305848,0.001137771,0.0007483407],"domain_scores_gemma":[0.9962392,0.00108689,0.0005239932,0.001428882,0.0003348386,0.0003862098],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8180576,0.03628063,0.02464811,0.0004204965,0.001702677,0.0009602985,0.001950325,0.00001596307,0.001736399,0.00004859312,0.002769532,0.1114094],"study_design_scores_gemma":[0.9507207,0.0237608,0.01573885,0.0008095573,0.0003998213,0.00001007335,0.00005085378,0.001079671,0.005158075,0.00003044437,0.001917507,0.0003236175],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950185,0.0001944475,0.00001588013,0.00004698371,0.0004123127,0.001621179,0.000107942,0.00006926106,0.00251348],"genre_scores_gemma":[0.9969229,0.0001015571,0.0005800708,0.0000675149,0.0016423,0.00003791624,0.0002469085,0.00007775187,0.00032313],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1326631,"threshold_uncertainty_score":0.9999653,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0379540287808474,"score_gpt":0.3492766603695263,"score_spread":0.3113226315886788,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}