{"id":"W2907903894","doi":"10.1111/acel.12889","title":"Circumventing senescence is associated with stem cell properties and metformin sensitivity","year":2019,"lang":"en","type":"article","venue":"Aging Cell","topic":"Telomeres, Telomerase, and Senescence","field":"Medicine","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Institute of Cancer Research; International Development Research Centre; Cancer Research Society; National Cancer Institute; Foundation for the National Institutes of Health","keywords":"Biology; Senescence; Stem cell; Cancer research; Cell biology; Carcinogenesis; Cancer stem cell; Cancer; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001602199,0.0002025761,0.0001603819,0.0002360077,0.000132012,0.000233289,0.00009120479,0.0002008716,0.0008376621],"category_scores_gemma":[0.000177559,0.00007666867,0.0001961572,0.000129061,0.0001534482,0.000185505,0.0001791432,0.0003232213,0.0001387295],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001559082,"about_ca_system_score_gemma":0.0001477436,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001840725,"about_ca_topic_score_gemma":0.0003157661,"domain_scores_codex":[0.9999257,0.000010231,0.00001304582,0.00001691665,0.00002076496,0.00001340505],"domain_scores_gemma":[0.9998026,0.00001742238,0.0001006138,0.00002007161,0.00001812757,0.0000411617],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001974743,0.00002932161,0.00320241,0.000055324,0.0000105809,0.0001801557,0.00002965101,0.00004603997,0.991474,0.0003128292,0.00004636983,0.004415768],"study_design_scores_gemma":[0.00002135269,0.001391861,0.07627279,0.00001572586,0.0000352702,0.002766161,0.0000645992,0.0005607749,0.9088706,0.0004272817,0.00956106,0.0000125275],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9916523,0.004314324,0.002439128,0.0001268754,0.0000236071,0.00002855805,0.0002778684,0.00005127314,0.001086052],"genre_scores_gemma":[0.9958462,0.0015734,0.001145874,0.000052516,0.00001645428,0.0000218682,0.0002262942,0.000005939273,0.001111427],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008376621,"threshold_uncertainty_score":0.002802253,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02028926204902963,"score_gpt":0.2055713243335672,"score_spread":0.1852820622845376,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}