{"id":"W2908043940","doi":"10.1002/cam4.1844","title":"Langerhans cell histiocytosis in adults is associated with a high prevalence of hematologic and solid malignancies","year":2018,"lang":"en","type":"article","venue":"Cancer Medicine","topic":"Histiocytic Disorders and Treatments","field":"Medicine","cited_by":57,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"National Cancer Institute; National Institutes of Health; Lymphoma Foundation","keywords":"Medicine; Langerhans cell histiocytosis; Malignancy; Cohort; Hematologic malignancy; Etoposide; Histiocyte; Internal medicine; Histiocytosis; Pediatrics; Chemotherapy; Disease; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002353222,0.0002060827,0.0002536497,0.0006137845,0.0003193591,0.0004225518,0.0001518667,0.0003323178,0.002018221],"category_scores_gemma":[0.001255711,0.000156873,0.0001132398,0.0009225673,0.0002710678,0.0004350288,0.0003043149,0.0003135914,0.0002831382],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001253366,"about_ca_system_score_gemma":0.0001804478,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006710133,"about_ca_topic_score_gemma":0.0009884932,"domain_scores_codex":[0.9997606,0.00003719961,0.00003713106,0.00006382194,0.00006107753,0.00004016188],"domain_scores_gemma":[0.9988674,0.000120626,0.0007428655,0.00003420817,0.00008124622,0.0001536604],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00002132718,0.000008438381,0.9971356,0.000008040971,0.000006199777,0.0005998824,0.00003541805,0.00001142718,0.0004080702,0.0000103917,0.000166001,0.001589062],"study_design_scores_gemma":[0.000002913785,0.00006391458,0.9891991,0.00001248606,0.00001075435,0.009797283,0.0002477907,0.00006254765,0.00011732,0.00003371944,0.0004492876,0.00000290043],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982521,0.0007272282,0.000111621,0.00007087812,0.000008550312,0.000008621056,0.0001576902,0.00001084515,0.000652438],"genre_scores_gemma":[0.9992942,0.0003160567,0.0001121496,0.00003628102,0.00002790479,0.000004897078,0.0001352508,0.000001757886,0.00007145195],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002018221,"threshold_uncertainty_score":0.006751597,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01364256015879931,"score_gpt":0.2698038136967363,"score_spread":0.256161253537937,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}