{"id":"W2908107400","doi":"10.1111/tra.12635","title":"Determinants of the assembly, integrity and maintenance of the endoplasmic reticulum‐peroxisome tether","year":2018,"lang":"en","type":"article","venue":"Traffic","topic":"Peroxisome Proliferator-Activated Receptors","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Peroxisome; Endoplasmic reticulum; Cell biology; Biology; Organelle; Saccharomyces cerevisiae; Membrane contact site; Membrane protein; Population; Yeast; Biochemistry; Integral membrane protein; Receptor; Membrane","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001631476,0.0001289648,0.0001592912,0.00001681404,0.00006984191,0.000006343366,0.0003477925,0.000150936,0.00001333975],"category_scores_gemma":[0.0001670546,0.0000700689,0.00008862881,0.0001223611,0.0006298501,0.000003567236,0.0001677006,0.0001681879,0.000002311424],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000008916989,"about_ca_system_score_gemma":0.00008066087,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001099811,"about_ca_topic_score_gemma":0.0001023621,"domain_scores_codex":[0.9991499,0.0001099408,0.000209894,0.0002190061,0.0001256431,0.0001855873],"domain_scores_gemma":[0.999251,0.00001621331,0.0001525476,0.0004443446,0.0001017777,0.0000341148],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004871034,0.00005117584,0.02833956,0.00002370503,0.00002253855,1.587293e-7,0.0001482861,0.000005852048,0.9695483,0.00002051749,0.0003067407,0.001484416],"study_design_scores_gemma":[0.0002994625,0.0001548304,0.01648386,0.00005918727,0.00001408826,0.00002039411,0.00007161998,0.0001224479,0.9813771,0.00001377191,0.001295808,0.00008743738],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9989789,0.0001377448,0.000006446399,0.0001115687,0.0002525488,0.000184409,0.00001521044,0.000006098086,0.0003071391],"genre_scores_gemma":[0.9994183,0.00005460527,0.00008695087,0.00008129634,0.00007058815,0.000007363024,8.603968e-7,0.00001640471,0.0002636519],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0118557,"threshold_uncertainty_score":0.2857327,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009365434111095652,"score_gpt":0.2447449335807393,"score_spread":0.2353794994696436,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}