{"id":"W2908114395","doi":"10.1093/brain/awy352","title":"Spatial distribution of multiple sclerosis lesions in the cervical spinal cord","year":2019,"lang":"en","type":"article","venue":"Brain","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":118,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Trois-Rivières; Montreal Neurological Institute and Hospital; Université de Montréal; Polytechnique Montréal","funders":"National Institute of Neurological Disorders and Stroke; National Eye Institute; Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; EMD Serono; National Multiple Sclerosis Society; International Progressive MS Alliance; Genentech; Rosetrees Trust; National Institutes of Health; Centre National de la Recherche Scientifique; Fonds de recherche du Québec – Nature et technologies; Stockholms Läns Landsting; Horizon 2020 Framework Programme; Svenska Sällskapet för Medicinsk Forskning; Ministero della Salute; Agence Nationale de la Recherche; College of Natural Resources and Sciences, Humboldt State University; University College London; Guarantors of Brain; Fondazione Italiana di Ricerca per la Sclerosi Laterale Amiotrofica; Natural Sciences and Engineering Research Council of Canada; Biogen; BioClinica; Vanderbilt University; Fondation pour l'Aide à la Recherche sur la Sclérose en Plaques; Fondazione Italiana Sclerosi Multipla; National Institute for Health and Care Research; Teva Pharmaceutical Industries; Sanofi","keywords":"Multiple sclerosis; Medicine; Lesion; White matter; Grey matter; Spinal cord; Expanded Disability Status Scale; Magnetic resonance imaging; Pathology; Central nervous system disease; Radiology; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003261853,0.0002325502,0.0003783269,0.001790224,0.0003245191,0.0004325179,0.0002513959,0.0002944157,0.001854453],"category_scores_gemma":[0.001714485,0.0001424359,0.0002444024,0.001098056,0.000337747,0.0001525344,0.0004046161,0.0001333647,0.0003063243],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004673147,"about_ca_system_score_gemma":0.0005357239,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.01499848,"about_ca_topic_score_gemma":0.02586004,"domain_scores_codex":[0.9996716,0.00004013404,0.00004520583,0.0001185686,0.00008878263,0.00003576813],"domain_scores_gemma":[0.9993834,0.0001808219,0.0002113004,0.00007490777,0.0001070262,0.00004250629],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0008076568,0.0000346888,0.9040185,0.0001884957,0.0002841384,0.0007649998,0.0005027555,0.001483771,0.06519046,0.000133411,0.0004901235,0.02610108],"study_design_scores_gemma":[0.000007175257,0.00005093887,0.996254,0.00001049443,0.00002976976,0.0009667757,0.00006747094,0.0007232782,0.001586676,0.00007558426,0.0002192667,0.000008700205],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978305,0.0002762475,0.0004139413,0.00001587369,0.000001233855,0.0000131439,0.0008971493,0.00003330248,0.0005187577],"genre_scores_gemma":[0.9979762,0.0001113689,0.0008606164,0.000007307392,0.000002618559,0.00002292569,0.000821359,0.000007886674,0.0001895911],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01499848,"threshold_uncertainty_score":0.02982235,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09865039538522351,"score_gpt":0.3424274357919952,"score_spread":0.2437770404067717,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}