{"id":"W2908114395","doi":"10.1093/brain/awy352","title":"Spatial distribution of multiple sclerosis lesions in the cervical spinal cord","year":2019,"lang":"en","type":"article","venue":"Brain","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":118,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Trois-Rivières; Montreal Neurological Institute and Hospital; Université de Montréal; Polytechnique Montréal","funders":"National Institute of Neurological Disorders and Stroke; National Eye Institute; Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; EMD Serono; National Multiple Sclerosis Society; International Progressive MS Alliance; Genentech; Rosetrees Trust; National Institutes of Health; Centre National de la Recherche Scientifique; Fonds de recherche du Québec – Nature et technologies; Stockholms Läns Landsting; Horizon 2020 Framework Programme; Svenska Sällskapet för Medicinsk Forskning; Ministero della Salute; Agence Nationale de la Recherche; College of Natural Resources and Sciences, Humboldt State University; University College London; Guarantors of Brain; Fondazione Italiana di Ricerca per la Sclerosi Laterale Amiotrofica; Natural Sciences and Engineering Research Council of Canada; Biogen; BioClinica; Vanderbilt University; Fondation pour l'Aide à la Recherche sur la Sclérose en Plaques; Fondazione Italiana Sclerosi Multipla; National Institute for Health and Care Research; Teva Pharmaceutical Industries; Sanofi","keywords":"Multiple sclerosis; Medicine; Lesion; White matter; Grey matter; Spinal cord; Expanded Disability Status Scale; Magnetic resonance imaging; Pathology; Central nervous system disease; Radiology; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005132598,0.00009210535,0.0002316295,0.00005586086,0.00004948635,0.000008925777,0.0001447087,0.00005784,0.0001366746],"category_scores_gemma":[0.001388805,0.00006012968,0.00008687396,0.0002600989,0.0001139186,0.00003592064,0.00009565627,0.0002188541,0.00007638278],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005973,"about_ca_system_score_gemma":0.00005218714,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000992534,"about_ca_topic_score_gemma":0.0004368222,"domain_scores_codex":[0.9987415,0.0001388035,0.000235442,0.0001841852,0.0004530146,0.0002470669],"domain_scores_gemma":[0.9990691,0.0004435549,0.00004837791,0.0003044381,0.00007781363,0.00005673644],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002736728,0.0008278564,0.7457687,0.000279853,0.0000548879,0.00001057421,0.0004968019,0.00001009101,0.08200231,0.0005692234,0.01067216,0.1565708],"study_design_scores_gemma":[0.001901653,0.0007017651,0.9915152,0.0002030271,0.000008085597,0.000002799962,0.00033536,0.001030381,0.001113597,0.00001546469,0.003115228,0.00005748424],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907681,0.00007126301,0.0002926892,0.007547188,0.00006009608,0.0006851943,0.00006383746,0.00001489332,0.0004967369],"genre_scores_gemma":[0.9992891,0.00004817669,0.0001055599,0.0002670345,0.0000825187,0.0000372286,0.00007167457,0.000007804011,0.00009089211],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2457464,"threshold_uncertainty_score":0.2452017,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09865039538522351,"score_gpt":0.3424274357919952,"score_spread":0.2437770404067717,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}