{"id":"W2908211253","doi":"10.1016/j.bbmt.2019.01.002","title":"Impact of High-Molecular-Risk Mutations on Transplantation Outcomes in Patients with Myelofibrosis","year":2019,"lang":"en","type":"article","venue":"Biology of Blood and Marrow Transplantation","topic":"Myeloproliferative Neoplasms: Diagnosis and Treatment","field":"Medicine","cited_by":62,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre","funders":"National Center for Advancing Translational Sciences; National Cancer Institute; National Heart, Lung, and Blood Institute","keywords":"Medicine; Myelofibrosis; Internal medicine; Oncology; Transplantation; International Prognostic Scoring System; Cohort; Hematopoietic stem cell transplantation; Disease; Framingham Risk Score; Myelodysplastic syndromes; Bone marrow","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005930917,0.0001452474,0.0003720807,0.0001804105,0.00001923036,0.000002394266,0.0000229836,0.00008966027,0.0000295465],"category_scores_gemma":[0.000006913881,0.00009602918,0.00006963811,0.00009977419,0.00005869014,0.00005068643,0.00000138112,0.00006860474,0.000001931938],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000117668,"about_ca_system_score_gemma":0.00003647087,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003215219,"about_ca_topic_score_gemma":0.00007164934,"domain_scores_codex":[0.9992361,0.00007242149,0.0002627654,0.000205905,0.0001074649,0.0001153254],"domain_scores_gemma":[0.9995027,0.0001465962,0.0001415421,0.00009451138,0.00007334071,0.00004136239],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.002056762,0.0008263448,0.9767137,0.0001860647,0.0003534304,0.000005618268,0.0004347092,0.0000756284,0.01774259,0.0004509958,3.796628e-7,0.001153757],"study_design_scores_gemma":[0.01079992,0.00577299,0.9331383,0.000176209,0.000619217,0.000005232765,0.00001323974,0.000004573064,0.04930236,0.00008399381,1.959871e-7,0.0000838339],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985671,0.00003710307,0.00007502769,0.00005481059,0.00002562365,0.0006291923,0.0005086359,0.000008335638,0.00009415502],"genre_scores_gemma":[0.9979461,0.000374323,0.0006431222,0.00002030706,0.000003089031,0.00002914054,0.0009681319,0.000009764629,0.000006013683],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04357549,"threshold_uncertainty_score":0.3915956,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004051658614116382,"score_gpt":0.2381446369449787,"score_spread":0.2340929783308623,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}