{"id":"W2908363006","doi":"10.1016/j.ijantimicag.2018.12.015","title":"Formation of Pseudomonas aeruginosa inhibition zone during tobramycin disk diffusion is due to transition from planktonic to biofilm mode of growth","year":2019,"lang":"en","type":"article","venue":"International Journal of Antimicrobial Agents","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Biofilm; Tobramycin; Pseudomonas aeruginosa; Chemistry; Agar; Microbiology; Agar diffusion test; Bacterial growth; Diffusion; Methylene blue; Bacteria; Agar plate; Incubation; Biophysics; Chromatography; Biology; Biochemistry; Escherichia coli","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001858308,0.0003750549,0.000495613,0.0002123459,0.0001658434,0.0004589952,0.0002876486,0.0004649152,0.0006760239],"category_scores_gemma":[0.0003911844,0.0003244529,0.0003194322,0.0002385676,0.0003258133,0.0003378201,0.0002861343,0.000663207,0.0003250771],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002446512,"about_ca_system_score_gemma":0.0002399958,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001558736,"about_ca_topic_score_gemma":0.0008343136,"domain_scores_codex":[0.9996573,0.0000535473,0.00002036481,0.00006655089,0.0001318561,0.00007046175],"domain_scores_gemma":[0.9996173,0.00009837442,0.0001209172,0.00004153384,0.00006978306,0.00005195678],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001156676,0.00002578593,0.0006001418,0.00004241237,0.000003761498,0.00006318665,0.00006918286,0.00004122187,0.9981754,0.00004100982,0.00002689433,0.0007953109],"study_design_scores_gemma":[0.0000144139,0.0003733036,0.02942926,0.00001490918,0.00001186179,0.0002892642,0.0001235301,0.001582327,0.9667062,0.00009604041,0.001341241,0.00001771878],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928318,0.001464368,0.003797587,0.0001248047,0.00001899966,0.00005799022,0.0003169637,0.0001220687,0.001265242],"genre_scores_gemma":[0.9952532,0.000427062,0.002463912,0.00004596509,0.000006010586,0.00006309764,0.0002094925,0.00001988766,0.001511401],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001558736,"threshold_uncertainty_score":0.003099322,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005529308474627364,"score_gpt":0.2262482335123726,"score_spread":0.2207189250377452,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}