{"id":"W2908583831","doi":"10.1200/jco.2013.31.15_suppl.5517","title":"A multicenter phase II study of bevacizumab (B) and temsirolimus (T) in women with recurrent epithelial ovarian cancer (OC): A study of the Mayo, Chicago, California, New York, Southeast, and Princess Margaret Phase II Consortia.","year":2013,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Ovarian cancer diagnosis and treatment","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Cancer Care Ontario; Juravinski Cancer Centre; Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Medicine; Temsirolimus; Neutropenia; Internal medicine; Gastroenterology; Adverse effect; Phases of clinical research; Cancer; Hypokalemia; Tolerability; Bevacizumab; Toxicity; Surgery; Chemotherapy; PI3K/AKT/mTOR pathway","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004032832,0.001058227,0.001317729,0.0004756139,0.0003921835,0.0006943356,0.0007054319,0.001017364,0.002916147],"category_scores_gemma":[0.001911687,0.0007101369,0.001096088,0.0004961428,0.0007424254,0.0007012004,0.0004094166,0.001909232,0.0006160352],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008928159,"about_ca_system_score_gemma":0.001833423,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001453333,"about_ca_topic_score_gemma":0.003210855,"domain_scores_codex":[0.9988173,0.0008057455,0.00005424734,0.0001401769,0.00007930183,0.0001031517],"domain_scores_gemma":[0.998292,0.0002707001,0.0003504237,0.0001101671,0.00008278893,0.0008938229],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.8159714,0.05240751,0.02956204,0.0005660307,0.001906717,0.0002241717,0.0003702885,0.001003446,0.02024983,0.0001522901,0.003046452,0.07453974],"study_design_scores_gemma":[0.6113102,0.3527178,0.03112488,0.00002931588,0.0007390274,0.0002192721,0.00007080792,0.0005138303,0.001020202,0.00008678532,0.002147533,0.0000202814],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931866,0.00182368,0.00039952,0.0003581831,0.00006291548,0.002521643,0.0007020466,0.00003884388,0.0009065269],"genre_scores_gemma":[0.9895191,0.001209083,0.001771523,0.0008846286,0.0001510071,0.003138094,0.001735936,0.0000278044,0.001562823],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004032832,"threshold_uncertainty_score":0.02132791,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07515892749311999,"score_gpt":0.4169801327173612,"score_spread":0.3418212052242413,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}