{"id":"W2908684026","doi":"10.1016/j.jmb.2019.01.008","title":"A Cell-Surface GH9 Endo-Glucanase Coordinates with Surface Glycan-Binding Proteins to Mediate Xyloglucan Uptake in the Gut Symbiont Bacteroides ovatus","year":2019,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Enzyme Production and Characterization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"British Columbia Knowledge Development Fund; Biotechnology and Biological Sciences Research Council; Canadian Institutes of Health Research; National Institutes of Health; National Institute of General Medical Sciences; Royal Society; Directorate for Biological Sciences; Canada Foundation for Innovation; University of Michigan","keywords":"Xyloglucan; Glycan; Biochemistry; Biology; Glycoside hydrolase; Bacteroides; Polysaccharide; Mutant; Gene; Genetics; Bacteria; Glycoprotein","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006311635,0.0002207389,0.0002911623,0.0001001348,0.00005095488,0.00003876484,0.0003772298,0.0001699967,0.00002931006],"category_scores_gemma":[0.0001013766,0.0001503763,0.00009626146,0.0002608494,0.00005950281,0.00001193688,0.00006729329,0.0002736368,0.00001517739],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004029636,"about_ca_system_score_gemma":0.0001627827,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003319277,"about_ca_topic_score_gemma":0.00004393658,"domain_scores_codex":[0.998427,0.0002875168,0.0004420943,0.0003288866,0.0001742886,0.0003401733],"domain_scores_gemma":[0.9989423,0.00002084267,0.0003715973,0.0003424327,0.0002130609,0.0001097946],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000327635,0.00009321648,0.01005748,0.00001904327,0.00005384741,0.00003350282,0.000180496,0.0005928121,0.9881762,0.00005610413,0.0002075634,0.0002021006],"study_design_scores_gemma":[0.001354368,0.001945558,0.006600925,0.00005097869,0.00003065704,0.0002196052,0.0005586524,0.00001420372,0.975574,0.00003034675,0.01335528,0.0002654846],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9951382,0.0006248667,0.001355887,0.001939071,0.0002997063,0.0004698106,0.00001687837,0.000005318382,0.0001503193],"genre_scores_gemma":[0.9966804,0.0001240124,0.002009541,0.0007385457,0.0001240872,0.000007292558,0.00006905078,0.00002755894,0.0002194595],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01314771,"threshold_uncertainty_score":0.6132168,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004892889224968995,"score_gpt":0.2322939715153984,"score_spread":0.2274010822904294,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}