{"id":"W2908684026","doi":"10.1016/j.jmb.2019.01.008","title":"A Cell-Surface GH9 Endo-Glucanase Coordinates with Surface Glycan-Binding Proteins to Mediate Xyloglucan Uptake in the Gut Symbiont Bacteroides ovatus","year":2019,"lang":"en","type":"article","venue":"Journal of Molecular Biology","topic":"Enzyme Production and Characterization","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":false,"ca_institutions":"Canada's Michael Smith Genome Sciences Centre; University of British Columbia","funders":"British Columbia Knowledge Development Fund; Biotechnology and Biological Sciences Research Council; Canadian Institutes of Health Research; National Institutes of Health; National Institute of General Medical Sciences; Royal Society; Directorate for Biological Sciences; Canada Foundation for Innovation; University of Michigan","keywords":"Xyloglucan; Glycan; Biochemistry; Biology; Glycoside hydrolase; Bacteroides; Polysaccharide; Mutant; Gene; Genetics; Bacteria; Glycoprotein","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001119007,0.0002648129,0.0002178068,0.00007355367,0.0001714419,0.0003924151,0.0002244769,0.0002752828,0.0003262892],"category_scores_gemma":[0.0001060343,0.0001664265,0.0002040404,0.00008899076,0.0002112171,0.0002120927,0.0002956776,0.0003817164,0.0003684368],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004678594,"about_ca_system_score_gemma":0.0002224579,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002009254,"about_ca_topic_score_gemma":0.001562739,"domain_scores_codex":[0.9999214,0.00001170791,0.000003754197,0.00001847186,0.00002022876,0.00002438609],"domain_scores_gemma":[0.9999312,0.00001111846,0.00001227943,0.000009252397,0.000012721,0.00002336181],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003924359,0.000005492728,0.0002209353,0.000006313993,0.000001373975,0.00003415595,0.00001031333,0.00003125789,0.9992849,0.00009385066,0.00001228953,0.0002599735],"study_design_scores_gemma":[0.00001350974,0.0001160282,0.01508573,0.00000287725,0.00001052979,0.0003272001,0.0001335676,0.003523802,0.9795601,0.00009989039,0.001119381,0.000007320731],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9973555,0.0001721212,0.001911505,0.00004841088,0.00001091263,0.000004489317,0.00004744357,0.00002326322,0.0004264529],"genre_scores_gemma":[0.996282,0.00008154316,0.001995447,0.0000199351,0.000003372985,0.000003396167,0.0001951931,0.00001559862,0.001403589],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002009254,"threshold_uncertainty_score":0.00399518,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004892889224968995,"score_gpt":0.2322939715153984,"score_spread":0.2274010822904294,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}