{"id":"W2908695821","doi":"10.3389/fendo.2018.00798","title":"A Linear Fragment of Unacylated Ghrelin (UAG6−13) Protects Against Myocardial Ischemia/Reperfusion Injury in Mice in a Growth Hormone Secretagogue Receptor-Independent Manner","year":2019,"lang":"en","type":"article","venue":"Frontiers in Endocrinology","topic":"Regulation of Appetite and Obesity","field":"Neuroscience","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa; Université de Sherbrooke; Université de Montréal","funders":"Université de Sherbrooke","keywords":"Ghrelin; Internal medicine; Endocrinology; Medicine; Growth hormone secretagogue receptor; Preload; Reperfusion injury; AMPK; Contractility; Antagonist; Ischemia; Receptor antagonist; Receptor; Protein kinase A; Hemodynamics; Chemistry; Kinase; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002881471,0.0002831572,0.0006212872,0.00079883,0.00003532078,0.00001129731,0.0004305741,0.0003008417,0.00004118408],"category_scores_gemma":[0.0002318226,0.000289729,0.0001054831,0.0007760656,0.0001535985,0.0002097481,0.0002784593,0.0007331753,0.00007072536],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000272183,"about_ca_system_score_gemma":0.0001014103,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003731262,"about_ca_topic_score_gemma":0.00005357899,"domain_scores_codex":[0.9970623,0.0003749363,0.0007272198,0.0007869761,0.0003780451,0.0006705867],"domain_scores_gemma":[0.9991882,0.00006755252,0.0002342406,0.000378538,0.00005192252,0.0000794733],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001157369,0.0003195032,0.09880295,0.00006001399,0.00001065025,0.0001079952,0.0005781824,0.001493004,0.8942536,0.000215762,0.0007944501,0.002206506],"study_design_scores_gemma":[0.003629977,0.0003646305,0.02723875,0.0001165995,0.000004510771,0.00001032573,0.0002318339,0.004820821,0.9610708,0.0004161086,0.001737288,0.0003583365],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960316,0.0002066739,0.0001605444,0.000420726,0.000878045,0.001170492,0.00001722418,0.00004552114,0.001069118],"genre_scores_gemma":[0.9969136,0.001000458,0.001391424,0.0002777231,0.00005667281,0.00007012852,0.00002099848,0.00003026826,0.000238794],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0715642,"threshold_uncertainty_score":0.9999555,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007917434479564006,"score_gpt":0.2253754875998952,"score_spread":0.2174580531203312,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}