{"id":"W2908900886","doi":"10.1371/journal.pone.0210665","title":"Identification of CD24 as a marker of Patched1 deleted medulloblastoma-initiating neural progenitor cells","year":2019,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Hedgehog Signaling Pathway Studies","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation; Hospital for Sick Children","funders":"Cancer Council Queensland; National Health and Medical Research Council","keywords":"Medulloblastoma; Sonic hedgehog; Biology; Population; Cancer research; CD24; Neural stem cell; Progenitor cell; CD15; Lineage markers; Pathology; Stem cell; Cancer stem cell; Medicine; Genetics; CD34","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001829792,0.0001094049,0.0002151301,0.00003833646,0.0000231691,0.00000584655,0.0001361684,0.00009011815,0.00002498262],"category_scores_gemma":[0.0001870771,0.0001107553,0.000071155,0.00008899495,0.00005323602,0.000003437477,0.00008350903,0.00005612239,0.00003041095],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007237667,"about_ca_system_score_gemma":0.00004449917,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009062689,"about_ca_topic_score_gemma":0.000003095957,"domain_scores_codex":[0.9989628,0.0000620225,0.0003653845,0.0002319061,0.0002243927,0.0001535627],"domain_scores_gemma":[0.9991241,0.00002741882,0.0002548088,0.0002880585,0.0002712289,0.00003442145],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006863628,0.0003166105,0.01072559,0.0002299702,0.0002903959,6.397299e-7,0.0001454998,0.00001183524,0.9880159,0.000003849299,0.00002018461,0.0001709125],"study_design_scores_gemma":[0.000292664,0.0002724024,0.002274864,0.00006753803,0.0000792783,7.869289e-7,0.0001433473,0.0004375063,0.9963004,0.000009349475,0.00001536954,0.0001065044],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9990044,0.0002748662,0.00003586085,0.00002974439,0.00005911845,0.0003298633,0.00003426731,0.00001121988,0.000220638],"genre_scores_gemma":[0.9989636,0.00002126996,0.000574144,0.00003140277,0.00007329059,0.00002659113,0.00003064423,0.00002165593,0.0002574343],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008450728,"threshold_uncertainty_score":0.4516472,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01899219078358544,"score_gpt":0.2269576433969649,"score_spread":0.2079654526133795,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}