{"id":"W2909005836","doi":"10.4049/jimmunol.1800833","title":"IL-33 Is a Negative Regulator of Vaccine-Induced Antigen-Specific Cellular Immunity","year":2019,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"IL-33, ST2, and ILC Pathways","field":"Immunology and Microbiology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Trinity College","funders":"","keywords":"Adjuvant; Immune system; Regulator; Immunity; CD8; Immunology; Acquired immune system; Cytokine; Cellular immunity; Vaccination; Alum; Biology; T cell; Antigen; Chemistry; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001730276,0.0005562206,0.0002200885,0.0001706004,0.0001113146,0.0002443197,0.0001070883,0.0002335809,0.001411484],"category_scores_gemma":[0.0001937979,0.0001595732,0.0001510437,0.00007702959,0.0002825425,0.0001746834,0.0001925902,0.0005861016,0.0003050995],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002071986,"about_ca_system_score_gemma":0.0001733123,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000133685,"about_ca_topic_score_gemma":0.0001776633,"domain_scores_codex":[0.9998192,0.00004914337,0.00001102607,0.00002347922,0.00005792228,0.0000391172],"domain_scores_gemma":[0.9998307,0.0000415561,0.00005570088,0.00002078723,0.00002493132,0.00002630807],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006295405,0.00000766503,0.0001157135,0.00002474453,0.000001620921,0.00003132527,0.000002518803,0.00006626396,0.9990839,0.00006723504,0.00002443601,0.000511581],"study_design_scores_gemma":[0.00001558099,0.0003554393,0.003872767,0.00001595042,0.00001526747,0.0003286947,0.00001939742,0.002034512,0.9907739,0.0001577347,0.00240621,0.00000455752],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9852958,0.003469787,0.008473956,0.0002180756,0.00007265891,0.00004991654,0.0003051868,0.0001312281,0.001983423],"genre_scores_gemma":[0.9967709,0.0005206352,0.001615447,0.00004964454,0.00001189689,0.00002328322,0.0001564415,0.00001043137,0.0008414063],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001411484,"threshold_uncertainty_score":0.00472194,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01528637709695599,"score_gpt":0.2186785020019817,"score_spread":0.2033921249050258,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}