{"id":"W2909009030","doi":"10.3138/canlivj.2018-0020","title":"Randomized clinical trial: Combination antiretroviral therapy with tenofovir-emtricitabine and lopinavir-ritonavir in patients with primary biliary cholangitis","year":2019,"lang":"en","type":"article","venue":"Canadian Liver Journal","topic":"Liver Diseases and Immunity","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Emtricitabine; Medicine; Internal medicine; Gastroenterology; Ritonavir; Ursodeoxycholic acid; Lopinavir; Clinical endpoint; Lopinavir/ritonavir; Placebo; Combination therapy; Randomized controlled trial; Viral load; Pharmacology; Immunology; Human immunodeficiency virus (HIV); Antiretroviral therapy; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004027398,0.002105613,0.005766246,0.0005660499,0.0006988855,0.001770959,0.001403692,0.003253815,0.0161095],"category_scores_gemma":[0.005059055,0.0009380731,0.002176489,0.0006714439,0.001808725,0.001608139,0.0006029595,0.003746782,0.001826677],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000908639,"about_ca_system_score_gemma":0.001995566,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001237462,"about_ca_topic_score_gemma":0.002262283,"domain_scores_codex":[0.9976341,0.001480205,0.0001873084,0.0003430215,0.0001302707,0.0002251936],"domain_scores_gemma":[0.9974096,0.0007902422,0.0005681298,0.0002349639,0.00027723,0.0007198058],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.993924,0.001579766,0.0001888058,0.0004399944,0.0004653787,0.00001574468,0.00001285582,0.00006621509,0.0004596451,0.00005885592,0.0003608339,0.002428032],"study_design_scores_gemma":[0.9883029,0.01084299,0.0002231761,0.00001892667,0.000143788,0.000008564086,0.000004555414,0.0001132252,0.00004953623,0.00005032994,0.0002384156,0.000003677225],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9118382,0.01631034,0.002616631,0.004314267,0.007061321,0.04469479,0.004919673,0.0004853156,0.007759502],"genre_scores_gemma":[0.9268088,0.005858972,0.005964521,0.004199071,0.002632552,0.03986195,0.003062628,0.00005968276,0.01155191],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0161095,"threshold_uncertainty_score":0.05389166,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01604859618932194,"score_gpt":0.2564456912943474,"score_spread":0.2403970951050255,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}