{"id":"W2909035282","doi":"10.1155/2019/6403274","title":"Detection of Active Caspase-3 in Mouse Models of Stroke and Alzheimer’s Disease with a Novel Dual Positron Emission Tomography/Fluorescent Tracer [<sup>68</sup>Ga]Ga-TC3-OGDOTA","year":2019,"lang":"en","type":"article","venue":"Contrast Media & Molecular Imaging","topic":"S100 Proteins and Annexins","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lawson Health Research Institute; Western University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Alzheimer's Society; Sanofi","keywords":"In vivo; Colocalization; Apoptosis; In vitro; Positron emission tomography; Chemistry; Neuroscience; Cell biology; Pathology; Medicine; Cancer research; Biology; Biochemistry; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005017687,0.0009981042,0.0005774766,0.0008523474,0.0001876843,0.0004364946,0.0005882602,0.001135388,0.0008815776],"category_scores_gemma":[0.0001797762,0.0004553367,0.0005549645,0.0004144301,0.0005579792,0.0005290703,0.0002232309,0.001423947,0.0003846144],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005537363,"about_ca_system_score_gemma":0.0003209934,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009457074,"about_ca_topic_score_gemma":0.001008031,"domain_scores_codex":[0.9997066,0.00004160566,0.00003159335,0.00008749255,0.00005968187,0.00007306075],"domain_scores_gemma":[0.9997861,0.00002353269,0.00007830701,0.00002596557,0.00003553767,0.00005060072],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001531867,0.00002221838,0.00008804107,0.00002998708,0.000007819024,0.00005072155,0.00001352264,0.0000448209,0.9988568,0.0001070003,0.00002733085,0.0005986542],"study_design_scores_gemma":[0.00005227227,0.0004814317,0.00128636,0.000009972571,0.00004823986,0.0005089696,0.00001998782,0.001207268,0.9947833,0.0001091851,0.001484481,0.000008418635],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9543945,0.004607146,0.03655786,0.0003396466,0.00008806626,0.0002494583,0.0009257495,0.0005559582,0.002281562],"genre_scores_gemma":[0.9464622,0.003037693,0.04321092,0.0002081306,0.00002254752,0.0005369136,0.001446152,0.0001675779,0.004907852],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001135388,"threshold_uncertainty_score":0.004017711,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005901399655021413,"score_gpt":0.2114267623141207,"score_spread":0.2055253626590993,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}