{"id":"W2909129451","doi":"10.1182/blood-2018-99-113062","title":"Genetic Characterization of ABT-199 Sensitivity in Human AML","year":2018,"lang":"en","type":"article","venue":"Blood","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Maisonneuve-Rosemont; Université de Montréal","funders":"","keywords":"NPM1; Myeloid leukemia; Gene mutation; Leukemia; Oncology; Mutation; Internal medicine; Concomitant; Cancer research; Cytarabine; Biology; Medicine; Gene; Genetics; Karyotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002073655,0.00006797296,0.0001755079,0.0001346697,0.00002630477,0.00000461012,0.00004106887,0.00006913568,0.00009432517],"category_scores_gemma":[0.00006124453,0.00006421409,0.00002730223,0.0002190032,0.0001092134,0.00003468471,0.0000449824,0.0001192974,0.0000444468],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000420268,"about_ca_system_score_gemma":0.00009093761,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001319118,"about_ca_topic_score_gemma":0.0000777815,"domain_scores_codex":[0.9992565,0.00005342239,0.0001742704,0.0001562068,0.0001835242,0.0001760673],"domain_scores_gemma":[0.9995245,0.00001853228,0.00004831572,0.0002427948,0.0001071961,0.00005868582],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00002799486,0.0002366948,0.1360349,0.00004226534,0.00001767236,0.00007408602,0.0002008402,6.885089e-8,0.8623802,0.00003365743,0.00002377045,0.0009278575],"study_design_scores_gemma":[0.001578989,0.0002017053,0.676837,0.00004141737,0.0000238667,0.00004150641,0.000009264611,0.0001090986,0.3209568,0.0000131272,0.0001456803,0.00004150291],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981093,0.000008584115,0.00009296156,0.0001551726,0.00002457144,0.0002336526,0.000006692284,0.00002069193,0.001348355],"genre_scores_gemma":[0.9988955,0.00001134124,0.0003692959,0.0001093735,0.0002805633,0.000005525676,0.00002838869,0.00001506022,0.0002848987],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.5414234,"threshold_uncertainty_score":0.2618575,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01649068347050372,"score_gpt":0.2881090579277114,"score_spread":0.2716183744572077,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}