{"id":"W2909129451","doi":"10.1182/blood-2018-99-113062","title":"Genetic Characterization of ABT-199 Sensitivity in Human AML","year":2018,"lang":"en","type":"article","venue":"Blood","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Maisonneuve-Rosemont; Université de Montréal","funders":"","keywords":"NPM1; Myeloid leukemia; Gene mutation; Leukemia; Oncology; Mutation; Internal medicine; Concomitant; Cancer research; Cytarabine; Biology; Medicine; Gene; Genetics; Karyotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008752528,0.0001216867,0.0001646906,0.0006941526,0.0001303117,0.0001949365,0.0001247981,0.0001829009,0.001428793],"category_scores_gemma":[0.0002712751,0.00007904068,0.0001772325,0.0004339762,0.0001340965,0.00004330021,0.0001373015,0.0001845868,0.0003948582],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002760547,"about_ca_system_score_gemma":0.0001853874,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002661766,"about_ca_topic_score_gemma":0.002827151,"domain_scores_codex":[0.9998672,0.00001336207,0.0000137814,0.00002219272,0.0000678947,0.00001540616],"domain_scores_gemma":[0.9998715,0.00003336423,0.00001924009,0.0000184161,0.0000352374,0.00002223251],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008943267,0.0000293797,0.004383445,0.00002539308,0.00001142662,0.0002233687,0.0000162963,0.0001765499,0.9921516,0.00006987437,0.0001173207,0.002705785],"study_design_scores_gemma":[0.00002679381,0.0007133476,0.125846,0.000008633041,0.00006276568,0.003591822,0.0000764201,0.002135484,0.8583921,0.000119339,0.009015246,0.00001198373],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9898183,0.00134028,0.002077148,0.00008629049,0.00001731943,0.0001571833,0.003876956,0.0000817402,0.002544754],"genre_scores_gemma":[0.992638,0.0006774591,0.001476015,0.00006196953,0.000005807145,0.00006911005,0.003808566,0.00001431534,0.001248741],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002661766,"threshold_uncertainty_score":0.005292535,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01649068347050372,"score_gpt":0.2881090579277114,"score_spread":0.2716183744572077,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}