{"id":"W2909144970","doi":"10.1016/s1474-4422(18)30371-5","title":"Investigation of frailty as a moderator of the relationship between neuropathology and dementia in Alzheimer's disease: a cross-sectional analysis of data from the Rush Memory and Aging Project","year":2019,"lang":"en","type":"article","venue":"The Lancet Neurology","topic":"Frailty in Older Adults","field":"Medicine","cited_by":313,"is_retracted":false,"has_abstract":false,"ca_institutions":"Nova Scotia Health Authority; Dalhousie University","funders":"National Institute on Aging; Canadian Institutes of Health Research","keywords":"Dementia; Neuropathology; Medicine; Alzheimer's disease; Cohort; Disease; Cohort study; Gerontology; Cross-sectional study; Clinical Dementia Rating; Psychology; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005702826,0.00008843476,0.0003679608,0.00009338548,0.00004692032,0.000006832229,0.0003092885,0.00006353795,0.00001366328],"category_scores_gemma":[0.0006138636,0.00005147679,0.00003782544,0.0003708902,0.0005272924,0.00007706715,0.0003052817,0.0002992362,6.587895e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000002747556,"about_ca_system_score_gemma":0.00008612189,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004511347,"about_ca_topic_score_gemma":0.000202214,"domain_scores_codex":[0.9984717,0.0006158458,0.000339729,0.000283369,0.0001687084,0.0001206508],"domain_scores_gemma":[0.9971086,0.001693291,0.0002621204,0.0008640934,0.00004668871,0.00002519166],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0002494517,0.000009708439,0.9974861,0.00002418989,0.0002697739,0.000001917405,0.0004906862,0.000115042,0.001113279,0.0001404115,0.00003718047,0.00006222917],"study_design_scores_gemma":[0.0008902198,0.00007775626,0.9922116,0.00001670227,0.001071606,0.000007497639,0.00001322697,0.004140499,0.0001298426,0.001388758,0.00001680618,0.00003543785],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9940002,0.0008218002,0.00001193363,0.004332323,0.00005104345,0.0004133793,0.000326193,0.000007235921,0.00003589145],"genre_scores_gemma":[0.9987671,0.00002393119,0.00004850795,0.000958156,0.00006522692,0.000008114012,0.000113338,0.000008660955,0.000006970888],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005274483,"threshold_uncertainty_score":0.2099162,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1689694459413566,"score_gpt":0.3658159027975547,"score_spread":0.1968464568561981,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}