{"id":"W2909157602","doi":"10.1016/j.virol.2019.01.017","title":"Enhancing the cross protective efficacy of live attenuated influenza virus vaccine by supplemented vaccination with M2 ectodomain virus-like particles","year":2019,"lang":"en","type":"article","venue":"Virology","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":19,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institute of Allergy and Infectious Diseases; National Institutes of Health","keywords":"Live attenuated influenza vaccine; Virology; Ectodomain; Vaccination; Antigenic drift; Biology; Virus; Nucleoprotein; Influenza A virus; Antigen; Antibody; Influenza vaccine; Immunology; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0008232328,0.0002910655,0.0006161134,0.0001712152,0.0002136012,0.0000221388,0.0002299188,0.0001513549,0.0007816554],"category_scores_gemma":[0.0006256658,0.0001823715,0.00008839004,0.0004827642,0.0001863574,0.000150671,0.0002026373,0.0004884026,0.0002650292],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001510912,"about_ca_system_score_gemma":0.0001276552,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001060188,"about_ca_topic_score_gemma":0.0009847668,"domain_scores_codex":[0.9973843,0.0003794449,0.0005930874,0.0004864873,0.0004890038,0.0006676433],"domain_scores_gemma":[0.9978195,0.0007073724,0.000312837,0.0005643212,0.0004954987,0.0001004332],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.008868328,0.0003832105,0.05834841,0.0001139874,0.0006347912,0.00002059516,0.002245948,0.0001505944,0.9276711,0.00006159215,0.0006750369,0.0008264501],"study_design_scores_gemma":[0.01049436,0.003310054,0.4899025,0.00005906565,0.0001284538,0.0000256593,0.0004426508,0.000319398,0.4919086,0.00006819594,0.003145887,0.0001951222],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954548,0.0005079156,0.0002460475,0.0007150115,0.00006256835,0.002728865,0.000087899,0.0000758579,0.0001210432],"genre_scores_gemma":[0.9979177,0.00004215836,0.0001435705,0.001358437,0.00005898927,0.0002691544,0.00003190074,0.00004517439,0.0001328855],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4357624,"threshold_uncertainty_score":0.8558578,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02527413560964437,"score_gpt":0.3487401353164244,"score_spread":0.32346599970678,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}