{"id":"W2909182124","doi":"10.1182/blood-2018-99-111514","title":"Efficacy and Safety of CPX-351 Versus 7+3 in a Subgroup of Older Patients with Newly Diagnosed Acute Myeloid Leukemia with Myelodysplasia-Related Changes (AML-MRC) Enrolled in a Phase 3 Study","year":2018,"lang":"en","type":"article","venue":"Blood","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Leukemia & Lymphoma Society of Canada","funders":"","keywords":"Medicine; Internal medicine; Cytarabine; Chemotherapy regimen; Oncology; Myelodysplastic syndromes; Decitabine; Regimen; Gastroenterology; Leukemia; Chemotherapy; Bone marrow","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001062631,0.0005317,0.001322831,0.0002198066,0.0003157655,0.0007105756,0.0003230365,0.0005650879,0.002199714],"category_scores_gemma":[0.0009495527,0.0002138676,0.001663682,0.0002550103,0.0002873161,0.0005978306,0.0002997298,0.001228207,0.0003200843],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005361392,"about_ca_system_score_gemma":0.0006233645,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004203055,"about_ca_topic_score_gemma":0.001138192,"domain_scores_codex":[0.9996737,0.0001116983,0.0000302119,0.00009600207,0.00003477449,0.0000535728],"domain_scores_gemma":[0.9993518,0.0001093062,0.0002022081,0.00004030467,0.00004024329,0.0002561839],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7859094,0.009343643,0.09954211,0.0006795373,0.003832328,0.0003530056,0.0002958923,0.000898833,0.01465169,0.0002071367,0.001432005,0.08285447],"study_design_scores_gemma":[0.2197755,0.3622625,0.3990702,0.0001828803,0.0062872,0.0009443162,0.0002941424,0.002718258,0.00249869,0.0006556094,0.005210776,0.00009999354],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997687,0.001371772,0.00008658073,0.00009450071,0.00002723251,0.0001741959,0.0002132987,0.000008975609,0.0003364123],"genre_scores_gemma":[0.9980287,0.0005129467,0.0001934952,0.0002374006,0.00004673313,0.0001851216,0.0005391878,0.000002944195,0.0002533779],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002199714,"threshold_uncertainty_score":0.007358789,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.010559426140119,"score_gpt":0.2763245240641133,"score_spread":0.2657650979239943,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}