{"id":"W2909306880","doi":"10.3390/molecules24020273","title":"Castanopsis lamontii Water Extract Shows Potential in Suppressing Pathogens, Lipopolysaccharide-Induced Inflammation and Oxidative Stress-Induced Cell Injury","year":2019,"lang":"en","type":"article","venue":"Molecules","topic":"Natural product bioactivities and synthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Agriculture and Agri-Food Canada","funders":"Chinese Academy of Agricultural Sciences; Natural Science Foundation of Zhejiang Province; National Natural Science Foundation of China","keywords":"Oxidative stress; Porphyromonas gingivalis; Antioxidant; Lipopolysaccharide; Inflammation; Reactive oxygen species; Microbiology; Pathogen; Anti-inflammatory; Chemistry; Antibacterial activity; Periodontitis; Traditional medicine; Bacteria; Biology; Pharmacology; Biochemistry; Medicine; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000071412,0.0005306491,0.0002356248,0.0005939096,0.0002506798,0.0001796216,0.0001386187,0.0002577846,0.00103948],"category_scores_gemma":[0.00006191975,0.00007834146,0.0002586315,0.0002557976,0.0001501707,0.0001781157,0.0001585013,0.0003407899,0.0001565656],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001955438,"about_ca_system_score_gemma":0.0003205261,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001117398,"about_ca_topic_score_gemma":0.003115376,"domain_scores_codex":[0.9999588,0.00000651414,0.000002978267,0.000006158759,0.00001579045,0.000009895493],"domain_scores_gemma":[0.9999666,0.000003815766,0.00001005374,0.000002758566,0.000006970136,0.000009889023],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001886501,0.00008060601,0.0002367859,0.0003927981,0.000007636273,0.0001111131,0.00001273717,0.00007551839,0.9897857,0.0001085281,0.00008851167,0.008911324],"study_design_scores_gemma":[0.00005941971,0.001426103,0.01775859,0.00007234892,0.00007268628,0.0003922157,0.0000683933,0.0005587571,0.9633319,0.000253611,0.01598513,0.00002081254],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9569131,0.02592086,0.004494318,0.0004577605,0.0001214287,0.0001378332,0.001157314,0.000181894,0.01061562],"genre_scores_gemma":[0.984658,0.006276185,0.003061386,0.0002845834,0.00003525985,0.00004832125,0.0007054374,0.00001391482,0.004916945],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001117398,"threshold_uncertainty_score":0.003477395,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006656358259099693,"score_gpt":0.2182058767473121,"score_spread":0.2115495184882124,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}