{"id":"W2909306880","doi":"10.3390/molecules24020273","title":"Castanopsis lamontii Water Extract Shows Potential in Suppressing Pathogens, Lipopolysaccharide-Induced Inflammation and Oxidative Stress-Induced Cell Injury","year":2019,"lang":"en","type":"article","venue":"Molecules","topic":"Natural product bioactivities and synthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Agriculture and Agri-Food Canada","funders":"Chinese Academy of Agricultural Sciences; Natural Science Foundation of Zhejiang Province; National Natural Science Foundation of China","keywords":"Oxidative stress; Porphyromonas gingivalis; Antioxidant; Lipopolysaccharide; Inflammation; Reactive oxygen species; Microbiology; Pathogen; Anti-inflammatory; Chemistry; Antibacterial activity; Periodontitis; Traditional medicine; Bacteria; Biology; Pharmacology; Biochemistry; Medicine; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001629339,0.000245079,0.0002255824,0.0001004362,0.00007699475,0.00008769187,0.0001387723,0.0002367051,0.00005043378],"category_scores_gemma":[0.00003208841,0.0001997766,0.00007749485,0.00004608153,0.00003288492,0.00003082443,0.0001641309,0.0001742518,0.00001107846],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002229381,"about_ca_system_score_gemma":0.00002970992,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001310839,"about_ca_topic_score_gemma":0.0001115459,"domain_scores_codex":[0.9985552,0.0001321843,0.0002627792,0.0005295548,0.0001687698,0.000351477],"domain_scores_gemma":[0.9994426,0.00001256348,0.00009260489,0.000330145,0.00005675353,0.00006534188],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001385452,0.00004193984,0.001169493,0.00003681444,0.00002647904,0.00001576626,0.0001599465,0.00001264854,0.9849213,0.000004622653,0.00001998786,0.01345242],"study_design_scores_gemma":[0.0003236725,0.0001698919,0.001363944,0.00002580227,0.00002074205,0.000006375961,0.0004007888,0.0001879374,0.9970102,0.00002916387,0.0001661625,0.0002953047],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986448,0.0002881907,0.00005827145,0.0001967694,0.0001769093,0.000302735,0.00005265946,0.0000136678,0.0002659418],"genre_scores_gemma":[0.9988447,0.00006220683,0.0004199974,0.00004388325,0.0001512791,0.00001413145,0.0001019519,0.00003339407,0.0003283958],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01315711,"threshold_uncertainty_score":0.8146651,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006656358259099693,"score_gpt":0.2182058767473121,"score_spread":0.2115495184882124,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}