{"id":"W2909547032","doi":"10.1038/s41588-018-0315-5","title":"PAX5-driven subtypes of B-progenitor acute lymphoblastic leukemia","year":2019,"lang":"en","type":"article","venue":"Nature Genetics","topic":"Acute Lymphoblastic Leukemia research","field":"Medicine","cited_by":617,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"National Institute of General Medical Sciences; National Cancer Institute","keywords":"Biology; Lymphoblastic Leukemia; Progenitor; Progenitor cell; Cancer research; Computational biology; Leukemia; Genetics; Immunology; Stem cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002117991,0.0002151651,0.0001837492,0.000635098,0.0003924337,0.0009627806,0.0003950047,0.0003584126,0.005389092],"category_scores_gemma":[0.0002652237,0.0001844575,0.0002024456,0.0004062945,0.0002688453,0.0003358622,0.0008586265,0.0007654119,0.0008214375],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000729325,"about_ca_system_score_gemma":0.0003168145,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001012041,"about_ca_topic_score_gemma":0.002361367,"domain_scores_codex":[0.9996846,0.00004740874,0.00002435912,0.00004878777,0.0001015302,0.00009343015],"domain_scores_gemma":[0.9998457,0.00002735971,0.00003704654,0.00003143886,0.00001109687,0.00004727825],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.001310904,0.0002390624,0.05594961,0.0002351185,0.0000998943,0.003401523,0.0004894744,0.001076172,0.8734544,0.0285491,0.003864799,0.03132998],"study_design_scores_gemma":[0.0003083622,0.001051738,0.2903831,0.0001209373,0.0002750203,0.05466276,0.002182479,0.007874828,0.5034421,0.01066507,0.1289818,0.00005179222],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9822183,0.001182883,0.001958671,0.0002031968,0.00002465356,0.00007526368,0.001121189,0.0001523806,0.01306341],"genre_scores_gemma":[0.9943515,0.0003647791,0.0007182516,0.00009270318,0.000007399063,0.00002992996,0.001118884,0.00004246832,0.003274059],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005389092,"threshold_uncertainty_score":0.01802832,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007594102956109199,"score_gpt":0.2752086812998694,"score_spread":0.2676145783437602,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}