{"id":"W2909547032","doi":"10.1038/s41588-018-0315-5","title":"PAX5-driven subtypes of B-progenitor acute lymphoblastic leukemia","year":2019,"lang":"en","type":"article","venue":"Nature Genetics","topic":"Acute Lymphoblastic Leukemia research","field":"Medicine","cited_by":617,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"National Institute of General Medical Sciences; National Cancer Institute","keywords":"Biology; Lymphoblastic Leukemia; Progenitor; Progenitor cell; Cancer research; Computational biology; Leukemia; Genetics; Immunology; Stem cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001393532,0.0002733214,0.0005283818,0.0002128997,0.00003848873,0.00001709355,0.000374855,0.0007436228,0.000342839],"category_scores_gemma":[0.0001677514,0.0002263856,0.0001888482,0.0004793721,0.0001517767,0.00004239741,0.0002008426,0.0006878171,0.0005024315],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008169551,"about_ca_system_score_gemma":0.001748772,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000106132,"about_ca_topic_score_gemma":0.00000331197,"domain_scores_codex":[0.9976109,0.00004464286,0.0003953238,0.0004664912,0.0009574118,0.0005252434],"domain_scores_gemma":[0.9980988,0.0001891821,0.0001423936,0.000832808,0.0004710281,0.0002657958],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002556045,0.0003254335,0.4628491,0.001399265,0.002009299,0.0005218684,0.0006099869,0.000663293,0.4925309,0.0005555026,0.0250548,0.01092444],"study_design_scores_gemma":[0.01898544,0.003618738,0.2480498,0.0006842029,0.001697068,0.001233573,0.0002620446,0.03762014,0.6466168,0.0004053926,0.03965008,0.001176705],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931725,0.001779832,0.0001587244,0.0001774769,0.0007210739,0.0006908125,0.00005470539,0.00006821589,0.003176711],"genre_scores_gemma":[0.9893253,0.0003412009,0.006614458,0.0004084753,0.0004505959,0.00001303669,0.00005728207,0.00007417591,0.002715478],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2147993,"threshold_uncertainty_score":0.9231737,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007594102956109199,"score_gpt":0.2752086812998694,"score_spread":0.2676145783437602,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}