{"id":"W2909706308","doi":"10.3390/metabo9010011","title":"Alteration of Metabolic Pathways in Osteoarthritis","year":2019,"lang":"en","type":"review","venue":"Metabolites","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":82,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"Canadian Institutes of Health Research","keywords":"Alkaptonuria; Metabolomics; Narrative review; Bioinformatics; Biology; Medicine; Computational biology; Genetics; Intensive care medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002692093,0.0004734825,0.003763875,0.0006445131,0.00001992849,0.00002139704,0.0001247482,0.0003326416,0.0002455462],"category_scores_gemma":[0.00009063632,0.0003760903,0.000755042,0.0005220774,0.00004009131,0.0001230891,0.00005356762,0.0002895603,0.0003563661],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002689966,"about_ca_system_score_gemma":0.0003227411,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000125849,"about_ca_topic_score_gemma":0.00001088413,"domain_scores_codex":[0.997681,0.0001842496,0.0009874529,0.0004699425,0.000322017,0.0003553994],"domain_scores_gemma":[0.9987301,0.0001144179,0.0003724295,0.0005927198,0.0000868702,0.0001035092],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00001328765,0.0001346088,0.00004643392,0.00680503,0.00007565635,0.00004102229,0.00006961608,4.564016e-8,0.0001527924,0.00740923,0.00001024792,0.985242],"study_design_scores_gemma":[0.002048936,0.0005261268,0.00003031387,0.01200271,0.002363853,0.0000961286,0.00001727681,6.818576e-7,0.001054463,0.0001155535,0.9814697,0.0002742721],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0005037552,0.9942544,0.000005096705,0.00000575685,0.0005161953,0.002027031,0.000204598,0.00003634525,0.002446894],"genre_scores_gemma":[0.0002533055,0.9963062,0.000797777,0.00002739222,0.0002293275,0.0002528321,0.0008092266,0.00007246887,0.001251472],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9849678,"threshold_uncertainty_score":0.9998691,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05733638203771396,"score_gpt":0.3160630716312712,"score_spread":0.2587266895935573,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}