{"id":"W2909736431","doi":"10.1002/tox.22705","title":"Coronarin D induces human oral cancer cell apoptosis though upregulate JNK1/2 signaling pathway","year":2019,"lang":"en","type":"article","venue":"Environmental Toxicology","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Surrey Memorial Hospital","funders":"Changhua Christian Hospital; National Science Council","keywords":"Apoptosis; Cancer; Cancer cell; Cancer research; Viability assay; Programmed cell death; Chemistry; Nasopharyngeal carcinoma; Biology; Medicine; Internal medicine; Biochemistry; Radiation therapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001031697,0.0002023994,0.0001844921,0.00002145586,0.0001154606,0.00001449402,0.0001642668,0.0003064859,0.002270124],"category_scores_gemma":[0.000001127273,0.0001956704,0.00009616139,0.00002643187,0.000075911,0.000008957802,0.0001861781,0.00009792948,0.00008278089],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008038449,"about_ca_system_score_gemma":0.00001829049,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004242042,"about_ca_topic_score_gemma":0.0000358311,"domain_scores_codex":[0.9988217,0.00007429103,0.0002079501,0.0004645051,0.0001239239,0.000307672],"domain_scores_gemma":[0.9995298,0.000006702488,0.0001121298,0.0002706113,0.000003972916,0.0000768092],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003273676,0.0001378807,0.002827832,0.000009155423,0.00003264354,0.000001221133,0.00006353645,0.0007004657,0.9921449,0.00008045937,0.00009223491,0.003876948],"study_design_scores_gemma":[0.0006879838,0.0005137524,0.007912828,0.000005541362,0.0000197125,0.000004382843,0.0001171381,0.00004914015,0.9718883,0.00008330715,0.0184596,0.0002582969],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969092,0.0008244978,0.00008418404,0.0000364851,0.00040506,0.0003037789,0.00002556242,0.00001407042,0.001397157],"genre_scores_gemma":[0.9899499,0.0001991405,0.0003200936,0.0002426602,0.0001830992,0.00004121498,0.0002388212,0.00003692582,0.008788127],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02025656,"threshold_uncertainty_score":0.9986419,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009829863813616052,"score_gpt":0.2309591225452241,"score_spread":0.221129258731608,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}