{"id":"W2909736431","doi":"10.1002/tox.22705","title":"Coronarin D induces human oral cancer cell apoptosis though upregulate JNK1/2 signaling pathway","year":2019,"lang":"en","type":"article","venue":"Environmental Toxicology","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Surrey Memorial Hospital","funders":"Changhua Christian Hospital; National Science Council","keywords":"Apoptosis; Cancer; Cancer cell; Cancer research; Viability assay; Programmed cell death; Chemistry; Nasopharyngeal carcinoma; Biology; Medicine; Internal medicine; Biochemistry; Radiation therapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006998707,0.000191877,0.0002120179,0.0001739242,0.0001560453,0.0001531357,0.00007078296,0.0001629451,0.001197742],"category_scores_gemma":[0.00006456104,0.00006071025,0.0002426154,0.0001425487,0.000120445,0.0001098336,0.0001513825,0.0003049573,0.000166188],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001787169,"about_ca_system_score_gemma":0.0002097777,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006810786,"about_ca_topic_score_gemma":0.000908917,"domain_scores_codex":[0.9999244,0.00001065378,0.000008348247,0.00001200916,0.00002015243,0.00002436903],"domain_scores_gemma":[0.9999709,0.000004566973,0.00000645095,0.000004581674,0.000007180911,0.000006303432],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005099415,0.0001339653,0.001212843,0.0001683577,0.00001637721,0.0001855071,0.0000489068,0.00006169177,0.9919032,0.00006860027,0.0001774861,0.005512951],"study_design_scores_gemma":[0.00005205783,0.001172821,0.02101169,0.00001746927,0.00004231577,0.0005141992,0.0001551966,0.0007717145,0.9710958,0.00007768535,0.005083133,0.000005836367],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947991,0.002847839,0.0005847096,0.00009801413,0.00002998144,0.00002294484,0.0001490581,0.00002473206,0.001443625],"genre_scores_gemma":[0.995702,0.001402367,0.0003839422,0.00007907545,0.000008035661,0.00002919593,0.0003001318,0.000003056877,0.002092196],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001197742,"threshold_uncertainty_score":0.004006863,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009829863813616052,"score_gpt":0.2309591225452241,"score_spread":0.221129258731608,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}